Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre

Methanolic extracts from the heart wood, stem bark, and stem wood of Ventilago harmandiana Pierre (Family Rhamnaceae) were assessed for anti-inflammatory effects using both acute and chronic inflammatory models. Analgesic and antipyretic activities of the extracts were also evaluated. It was found t...

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Main Authors: Panthong A., Kanjanapothi D., Taesotikul T., Phankummoon A., Panthong K., Reutrakul V.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-2342437276&partnerID=40&md5=19c770622c190ad31dff2252f9865bab
http://www.ncbi.nlm.nih.gov/pubmed/15120445
http://cmuir.cmu.ac.th/handle/6653943832/4216
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-42162014-08-30T02:35:48Z Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre Panthong A. Kanjanapothi D. Taesotikul T. Phankummoon A. Panthong K. Reutrakul V. Methanolic extracts from the heart wood, stem bark, and stem wood of Ventilago harmandiana Pierre (Family Rhamnaceae) were assessed for anti-inflammatory effects using both acute and chronic inflammatory models. Analgesic and antipyretic activities of the extracts were also evaluated. It was found that all extracts possessed strong inhibitory effects on the acute phase of inflammation as seen in ethyl phenylpropiolate (EPP)- and arachidonic acid (AA)-induced ear edema as well as in carrageenin-induced paw edema in rats. The extracts elicited only weak inhibitory activity on cotton pellet-induced granuloma formation, a subchronic inflammatory model. In the analgesic test, all extracts exerted pronounced inhibitory activity in acetic acid-induced writhing response but showed only weak effects in the tail-flick test. The extracts also showed excellent antipyretic activity on yeast-induced hyperthermia in rats. © 2004 Published by Elsevier Ireland Ltd. 2014-08-30T02:35:48Z 2014-08-30T02:35:48Z 2004 Article 03788741 10.1016/j.jep.2003.12.025 15120445 JOETD http://www.scopus.com/inward/record.url?eid=2-s2.0-2342437276&partnerID=40&md5=19c770622c190ad31dff2252f9865bab http://www.ncbi.nlm.nih.gov/pubmed/15120445 http://cmuir.cmu.ac.th/handle/6653943832/4216 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description Methanolic extracts from the heart wood, stem bark, and stem wood of Ventilago harmandiana Pierre (Family Rhamnaceae) were assessed for anti-inflammatory effects using both acute and chronic inflammatory models. Analgesic and antipyretic activities of the extracts were also evaluated. It was found that all extracts possessed strong inhibitory effects on the acute phase of inflammation as seen in ethyl phenylpropiolate (EPP)- and arachidonic acid (AA)-induced ear edema as well as in carrageenin-induced paw edema in rats. The extracts elicited only weak inhibitory activity on cotton pellet-induced granuloma formation, a subchronic inflammatory model. In the analgesic test, all extracts exerted pronounced inhibitory activity in acetic acid-induced writhing response but showed only weak effects in the tail-flick test. The extracts also showed excellent antipyretic activity on yeast-induced hyperthermia in rats. © 2004 Published by Elsevier Ireland Ltd.
format Article
author Panthong A.
Kanjanapothi D.
Taesotikul T.
Phankummoon A.
Panthong K.
Reutrakul V.
spellingShingle Panthong A.
Kanjanapothi D.
Taesotikul T.
Phankummoon A.
Panthong K.
Reutrakul V.
Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre
author_facet Panthong A.
Kanjanapothi D.
Taesotikul T.
Phankummoon A.
Panthong K.
Reutrakul V.
author_sort Panthong A.
title Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre
title_short Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre
title_full Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre
title_fullStr Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre
title_full_unstemmed Anti-inflammatory activity of methanolic extracts from Ventilago harmandiana Pierre
title_sort anti-inflammatory activity of methanolic extracts from ventilago harmandiana pierre
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-2342437276&partnerID=40&md5=19c770622c190ad31dff2252f9865bab
http://www.ncbi.nlm.nih.gov/pubmed/15120445
http://cmuir.cmu.ac.th/handle/6653943832/4216
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