Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus

© 2016 Taylor & Francis Group, LLC. Purpose: To report on clinical manifestations of Purtscher-like retinopathy (PLR) associated with systemic lupus erythematosus (SLE) and visual outcomes. Methods: We performed a retrospective cohort study of 11 patients (21 affected eyes) with PLR in SLE. Re...

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Main Authors: Kunavisarut P., Pathanapitoon K., Rothova A.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84957963070&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42165
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-421652017-09-28T04:25:32Z Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus Kunavisarut P. Pathanapitoon K. Rothova A. © 2016 Taylor & Francis Group, LLC. Purpose: To report on clinical manifestations of Purtscher-like retinopathy (PLR) associated with systemic lupus erythematosus (SLE) and visual outcomes. Methods: We performed a retrospective cohort study of 11 patients (21 affected eyes) with PLR in SLE. Results: All patients were treated with systemic corticosteroids ± immunosuppressive agents. Ocular therapy included intravitreal injections with bevacizumab in 18/21 eyes and posterior sub-Tenon injections with triamcinolone acetonide 13/21 eyes. Panretinal photocoagulation (PRP) was performed in 19/21 eyes and pars plana vitrectomy was required in 5/21 eyes. Visual improvement was found at follow-up of 3 and 6 months (p = 0.05). Poor visual outcome was associated with presence of neovascularizations at onset (p = 0.009), development of vitreous hemorrhage during PRP (p = 0.015), and active status of SLE after onset of PLR (p = 0.029). Conclusions: PLR might manifest as a devastating complication of SLE. We recommend treating any systemic activity of SLE and starting an early ocular treatment. 2017-09-28T04:25:32Z 2017-09-28T04:25:32Z 2016-01-02 Journal 09273948 2-s2.0-84957963070 10.3109/09273948.2014.932816 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84957963070&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42165
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description © 2016 Taylor & Francis Group, LLC. Purpose: To report on clinical manifestations of Purtscher-like retinopathy (PLR) associated with systemic lupus erythematosus (SLE) and visual outcomes. Methods: We performed a retrospective cohort study of 11 patients (21 affected eyes) with PLR in SLE. Results: All patients were treated with systemic corticosteroids ± immunosuppressive agents. Ocular therapy included intravitreal injections with bevacizumab in 18/21 eyes and posterior sub-Tenon injections with triamcinolone acetonide 13/21 eyes. Panretinal photocoagulation (PRP) was performed in 19/21 eyes and pars plana vitrectomy was required in 5/21 eyes. Visual improvement was found at follow-up of 3 and 6 months (p = 0.05). Poor visual outcome was associated with presence of neovascularizations at onset (p = 0.009), development of vitreous hemorrhage during PRP (p = 0.015), and active status of SLE after onset of PLR (p = 0.029). Conclusions: PLR might manifest as a devastating complication of SLE. We recommend treating any systemic activity of SLE and starting an early ocular treatment.
format Journal
author Kunavisarut P.
Pathanapitoon K.
Rothova A.
spellingShingle Kunavisarut P.
Pathanapitoon K.
Rothova A.
Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus
author_facet Kunavisarut P.
Pathanapitoon K.
Rothova A.
author_sort Kunavisarut P.
title Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus
title_short Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus
title_full Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus
title_fullStr Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus
title_full_unstemmed Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus
title_sort purtscher-like retinopathy associated with systemic lupus erythematosus
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84957963070&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42165
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