How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination
Aim: To present the experience of management of second trimester pregnancy termination by misoprostol after failure to abort within 48 h of its use. Material and Methods: A retrospective, cohort descriptive study was carried out in the Department of Obstetrics and Gynecology, Faculty of Medicine, Ch...
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th-cmuir.6653943832-42222014-08-30T02:35:48Z How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination Pongsatha S. Tongsong T. Aim: To present the experience of management of second trimester pregnancy termination by misoprostol after failure to abort within 48 h of its use. Material and Methods: A retrospective, cohort descriptive study was carried out in the Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University Thailand between 1998 and 2010. All women at 14-28 weeks of gestation who failed to abort using misoprostol within 48 h were included. Management of failed pregnancy termination among these women is described here. Results: Of a total of 680 women undergoing termination of pregnancy, 68 (10%) failed to abort. Mean maternal age was 28.71 years and mean gestational age was 19.91 weeks. Further management after failure included additional administration of misoprostol only (19.1%), modified condom balloon technique only (17.7%), modified condom balloon technique plus other methods (16.1%), while 47.1% needed only oxytocin as necessary. The mean interval between initiation of termination and delivery was 96.97 h. Conclusion: Failure of pregnancy termination using misoprostol can be successfully managed by introducing additional misoprostol, modified condom balloon technique and oxytocin infusion. These methods should be considered before proceeding to hysterotomy. © 2012 The Authors. 2014-08-30T02:35:48Z 2014-08-30T02:35:48Z 2013 Article 13418076 10.1111/j.1447-0756.2012.01911.x 22691227 JOGRF http://www.scopus.com/inward/record.url?eid=2-s2.0-84875723465&partnerID=40&md5=ba50af38982ebf18eba28baa68fdafb8 http://cmuir.cmu.ac.th/handle/6653943832/4222 English |
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Aim: To present the experience of management of second trimester pregnancy termination by misoprostol after failure to abort within 48 h of its use. Material and Methods: A retrospective, cohort descriptive study was carried out in the Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University Thailand between 1998 and 2010. All women at 14-28 weeks of gestation who failed to abort using misoprostol within 48 h were included. Management of failed pregnancy termination among these women is described here. Results: Of a total of 680 women undergoing termination of pregnancy, 68 (10%) failed to abort. Mean maternal age was 28.71 years and mean gestational age was 19.91 weeks. Further management after failure included additional administration of misoprostol only (19.1%), modified condom balloon technique only (17.7%), modified condom balloon technique plus other methods (16.1%), while 47.1% needed only oxytocin as necessary. The mean interval between initiation of termination and delivery was 96.97 h. Conclusion: Failure of pregnancy termination using misoprostol can be successfully managed by introducing additional misoprostol, modified condom balloon technique and oxytocin infusion. These methods should be considered before proceeding to hysterotomy. © 2012 The Authors. |
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Article |
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Pongsatha S. Tongsong T. |
spellingShingle |
Pongsatha S. Tongsong T. How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination |
author_facet |
Pongsatha S. Tongsong T. |
author_sort |
Pongsatha S. |
title |
How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination |
title_short |
How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination |
title_full |
How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination |
title_fullStr |
How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination |
title_full_unstemmed |
How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination |
title_sort |
how to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination |
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2014 |
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http://www.scopus.com/inward/record.url?eid=2-s2.0-84875723465&partnerID=40&md5=ba50af38982ebf18eba28baa68fdafb8 http://cmuir.cmu.ac.th/handle/6653943832/4222 |
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