Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy
© 2016 BMJ Publishing Group Ltd. This report is aimed to describe a life-threatening case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis secondary to ovarian teratoma with rapid recovery in 1 day after the removal of the tumour. A 23-year-old woman presented with sudden headache, persona...
Saved in:
Main Authors: | , , , |
---|---|
Format: | Journal |
Published: |
2017
|
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84982243120&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42226 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Chiang Mai University |
id |
th-cmuir.6653943832-42226 |
---|---|
record_format |
dspace |
spelling |
th-cmuir.6653943832-422262017-09-28T04:25:51Z Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy Tantipalakorn C. Soontornpun A. Pongsuvareeyakul T. Tongsong T. © 2016 BMJ Publishing Group Ltd. This report is aimed to describe a life-threatening case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis secondary to ovarian teratoma with rapid recovery in 1 day after the removal of the tumour. A 23-year-old woman presented with sudden headache, personality changes and seizure. After neurological assessment, limbic or herpes encephalitis was provisionally diagnosed and treated with intravenous immunoglobulin, acyclovir and steroids. The patient had progressive severe neurological symptoms, requiring prolonged intubation and mechanical ventilation. An anti-NMDAR antibody test revealed positive in serum and cerebrospinal fluid at 3 weeks of admission. Pelvic ultrasound examination and CT scan revealed bilateral small ovarian teratomas. Bilateral ovarian cystectomy was performed by open surgery. The patient showed rapid improvement and no longer needed intubation 2 days after the operation. In conclusion, we described a catastrophic case of ovarian teratoma-associated encephalitis with delayed diagnosis but rapid recovery after ovarian cystectomy. This information can probably be helpful to neurologists and gynaecologists. 2017-09-28T04:25:51Z 2017-09-28T04:25:51Z 2016-01-01 Journal 2-s2.0-84982243120 10.1136/bcr-2016-216484 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84982243120&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42226 |
institution |
Chiang Mai University |
building |
Chiang Mai University Library |
country |
Thailand |
collection |
CMU Intellectual Repository |
description |
© 2016 BMJ Publishing Group Ltd. This report is aimed to describe a life-threatening case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis secondary to ovarian teratoma with rapid recovery in 1 day after the removal of the tumour. A 23-year-old woman presented with sudden headache, personality changes and seizure. After neurological assessment, limbic or herpes encephalitis was provisionally diagnosed and treated with intravenous immunoglobulin, acyclovir and steroids. The patient had progressive severe neurological symptoms, requiring prolonged intubation and mechanical ventilation. An anti-NMDAR antibody test revealed positive in serum and cerebrospinal fluid at 3 weeks of admission. Pelvic ultrasound examination and CT scan revealed bilateral small ovarian teratomas. Bilateral ovarian cystectomy was performed by open surgery. The patient showed rapid improvement and no longer needed intubation 2 days after the operation. In conclusion, we described a catastrophic case of ovarian teratoma-associated encephalitis with delayed diagnosis but rapid recovery after ovarian cystectomy. This information can probably be helpful to neurologists and gynaecologists. |
format |
Journal |
author |
Tantipalakorn C. Soontornpun A. Pongsuvareeyakul T. Tongsong T. |
spellingShingle |
Tantipalakorn C. Soontornpun A. Pongsuvareeyakul T. Tongsong T. Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy |
author_facet |
Tantipalakorn C. Soontornpun A. Pongsuvareeyakul T. Tongsong T. |
author_sort |
Tantipalakorn C. |
title |
Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy |
title_short |
Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy |
title_full |
Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy |
title_fullStr |
Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy |
title_full_unstemmed |
Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy |
title_sort |
rapid recovery from catastrophic paraneoplastic anti-nmdar encephalitis secondary to an ovarian teratoma following ovarian cystectomy |
publishDate |
2017 |
url |
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84982243120&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42226 |
_version_ |
1681422149027364864 |