Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy

© 2016 BMJ Publishing Group Ltd. This report is aimed to describe a life-threatening case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis secondary to ovarian teratoma with rapid recovery in 1 day after the removal of the tumour. A 23-year-old woman presented with sudden headache, persona...

Full description

Saved in:
Bibliographic Details
Main Authors: Tantipalakorn C., Soontornpun A., Pongsuvareeyakul T., Tongsong T.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84982243120&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42226
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
id th-cmuir.6653943832-42226
record_format dspace
spelling th-cmuir.6653943832-422262017-09-28T04:25:51Z Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy Tantipalakorn C. Soontornpun A. Pongsuvareeyakul T. Tongsong T. © 2016 BMJ Publishing Group Ltd. This report is aimed to describe a life-threatening case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis secondary to ovarian teratoma with rapid recovery in 1 day after the removal of the tumour. A 23-year-old woman presented with sudden headache, personality changes and seizure. After neurological assessment, limbic or herpes encephalitis was provisionally diagnosed and treated with intravenous immunoglobulin, acyclovir and steroids. The patient had progressive severe neurological symptoms, requiring prolonged intubation and mechanical ventilation. An anti-NMDAR antibody test revealed positive in serum and cerebrospinal fluid at 3 weeks of admission. Pelvic ultrasound examination and CT scan revealed bilateral small ovarian teratomas. Bilateral ovarian cystectomy was performed by open surgery. The patient showed rapid improvement and no longer needed intubation 2 days after the operation. In conclusion, we described a catastrophic case of ovarian teratoma-associated encephalitis with delayed diagnosis but rapid recovery after ovarian cystectomy. This information can probably be helpful to neurologists and gynaecologists. 2017-09-28T04:25:51Z 2017-09-28T04:25:51Z 2016-01-01 Journal 2-s2.0-84982243120 10.1136/bcr-2016-216484 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84982243120&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42226
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description © 2016 BMJ Publishing Group Ltd. This report is aimed to describe a life-threatening case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis secondary to ovarian teratoma with rapid recovery in 1 day after the removal of the tumour. A 23-year-old woman presented with sudden headache, personality changes and seizure. After neurological assessment, limbic or herpes encephalitis was provisionally diagnosed and treated with intravenous immunoglobulin, acyclovir and steroids. The patient had progressive severe neurological symptoms, requiring prolonged intubation and mechanical ventilation. An anti-NMDAR antibody test revealed positive in serum and cerebrospinal fluid at 3 weeks of admission. Pelvic ultrasound examination and CT scan revealed bilateral small ovarian teratomas. Bilateral ovarian cystectomy was performed by open surgery. The patient showed rapid improvement and no longer needed intubation 2 days after the operation. In conclusion, we described a catastrophic case of ovarian teratoma-associated encephalitis with delayed diagnosis but rapid recovery after ovarian cystectomy. This information can probably be helpful to neurologists and gynaecologists.
format Journal
author Tantipalakorn C.
Soontornpun A.
Pongsuvareeyakul T.
Tongsong T.
spellingShingle Tantipalakorn C.
Soontornpun A.
Pongsuvareeyakul T.
Tongsong T.
Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy
author_facet Tantipalakorn C.
Soontornpun A.
Pongsuvareeyakul T.
Tongsong T.
author_sort Tantipalakorn C.
title Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy
title_short Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy
title_full Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy
title_fullStr Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy
title_full_unstemmed Rapid recovery from catastrophic paraneoplastic anti-NMDAR encephalitis secondary to an ovarian teratoma following ovarian cystectomy
title_sort rapid recovery from catastrophic paraneoplastic anti-nmdar encephalitis secondary to an ovarian teratoma following ovarian cystectomy
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84982243120&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42226
_version_ 1681422149027364864