Detection of Hb H disease genotypes common in Northern Thailand by quantitative real-time polymerase chain reaction and high resolution melting analyses

• المؤلفون الرئيسيون: Seeratanachot T., Sanguansermsri T., Shimbhu D.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-84887215064&partnerID=40&md5=daea25c7bcdba940b383ed9a588f8d0a; http://cmuir.cmu.ac.th/handle/6653943832/4235

We used quantitative real-time polymerase chain reaction (qPCR) and high resolution melting (HRM) analyses for the detection of the common α-thalassemia (α-thal) genotypes in 40 northern Thai Hb H (β4) patients. The α0-thal [-SEA (Southeast Asian) deletion] was detected by a multiplex gap real-time...