Myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software

To assess the iron overload in human tissue especially in the heart of transfusion-dependent thalassemia patients using cardiac magnetic resonance imaging (CMRI) technique has been widely used to evaluate cardiac iron deposition because of its non-invasive procedure. The iron measure from this techn...

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Main Authors: Boonchieng E., Duangchaemkarn K.
Format: Conference Proceeding
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875085558&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42711
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-427112017-09-28T06:36:12Z Myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software Boonchieng E. Duangchaemkarn K. To assess the iron overload in human tissue especially in the heart of transfusion-dependent thalassemia patients using cardiac magnetic resonance imaging (CMRI) technique has been widely used to evaluate cardiac iron deposition because of its non-invasive procedure. The iron measure from this technique is represent as T2*(T2 Star) value. Cardiac T2*software was developed. The software was measuring T2*value from DICOM image with two algorithm processing components; regions of interest (ROI) identification, and T2*optimization. The software preliminary testing was performed using test cases DICOM image, three times repeating, from both healthy volunteer and thalassemia patient with cardiac iron overload, then compared T2*value with the reference tool (CMRtools with ThalassemiaTools plug-in). Mean T2*value analyzed from healthy volunteer CMRI was 22.36 (±0.94) and 37.10 (±1.62), respectively. While the mean T2*value analyzed from thalassemia patients CMRI was 15.52 (±0.85) and 18.67 (±1.15) in reference software and CMUT2Star software respectively. In conclusion, CMUT2Star produced a higher T2*value than the reference tool. Software has no any errors and no conflict with testing platform. The algorithm in T2*optimization component need to be adjusted in order to produce the accuracy and robust T2*value. ©2012 IEEE. 2017-09-28T06:36:12Z 2017-09-28T06:36:12Z 2012-12-01 Conference Proceeding 2-s2.0-84875085558 10.1109/BMEiCon.2012.6465497 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875085558&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42711
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description To assess the iron overload in human tissue especially in the heart of transfusion-dependent thalassemia patients using cardiac magnetic resonance imaging (CMRI) technique has been widely used to evaluate cardiac iron deposition because of its non-invasive procedure. The iron measure from this technique is represent as T2*(T2 Star) value. Cardiac T2*software was developed. The software was measuring T2*value from DICOM image with two algorithm processing components; regions of interest (ROI) identification, and T2*optimization. The software preliminary testing was performed using test cases DICOM image, three times repeating, from both healthy volunteer and thalassemia patient with cardiac iron overload, then compared T2*value with the reference tool (CMRtools with ThalassemiaTools plug-in). Mean T2*value analyzed from healthy volunteer CMRI was 22.36 (±0.94) and 37.10 (±1.62), respectively. While the mean T2*value analyzed from thalassemia patients CMRI was 15.52 (±0.85) and 18.67 (±1.15) in reference software and CMUT2Star software respectively. In conclusion, CMUT2Star produced a higher T2*value than the reference tool. Software has no any errors and no conflict with testing platform. The algorithm in T2*optimization component need to be adjusted in order to produce the accuracy and robust T2*value. ©2012 IEEE.
format Conference Proceeding
author Boonchieng E.
Duangchaemkarn K.
spellingShingle Boonchieng E.
Duangchaemkarn K.
Myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software
author_facet Boonchieng E.
Duangchaemkarn K.
author_sort Boonchieng E.
title Myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software
title_short Myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software
title_full Myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software
title_fullStr Myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software
title_full_unstemmed Myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software
title_sort myocardial iron measurement in thalassemia using cardiac magnetic resonance image processing software
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875085558&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42711
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