Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis

Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis

Chronic histiocytic intervillositis (CHI) is an infrequent inflammatory placental disorder associated with unfavorable pregnancy outcomes and a high rate of recurrence. This disorder is thought to reflect a maternal delayed hypersensitivity response to fetal antigen(s) in placental tissue. We report...

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Main Authors: Taweevisit M., Sukpan K., Siriaunkgul S., Thorner P.
Format: Journal
Published: 2017
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867703194&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42720
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-427202017-09-28T06:37:56Z Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis Taweevisit M. Sukpan K. Siriaunkgul S. Thorner P. Chronic histiocytic intervillositis (CHI) is an infrequent inflammatory placental disorder associated with unfavorable pregnancy outcomes and a high rate of recurrence. This disorder is thought to reflect a maternal delayed hypersensitivity response to fetal antigen(s) in placental tissue. We report a case of a 20-week-gestation hydropic fetus in which the placenta showed chronic histiocytic intervillositis with cytomegalovirus placentitis. Immunophenotyping studies supported a delayed hypersensitivity response. This is the first report of these two diseases co-occurring, raising the possibility of a relationship between chronic histiocytic intervillositis and infection. Chronic histiocytic intervillositis may represent an idiosyncratic immune response, in this case to cytomegalovirus. Copyright © Informa Healthcare USA, Inc. 2017-09-28T06:37:56Z 2017-09-28T06:37:56Z 2012-12-01 Journal 15513815 2-s2.0-84867703194 10.3109/15513815.2012.659405 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867703194&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/42720
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description Chronic histiocytic intervillositis (CHI) is an infrequent inflammatory placental disorder associated with unfavorable pregnancy outcomes and a high rate of recurrence. This disorder is thought to reflect a maternal delayed hypersensitivity response to fetal antigen(s) in placental tissue. We report a case of a 20-week-gestation hydropic fetus in which the placenta showed chronic histiocytic intervillositis with cytomegalovirus placentitis. Immunophenotyping studies supported a delayed hypersensitivity response. This is the first report of these two diseases co-occurring, raising the possibility of a relationship between chronic histiocytic intervillositis and infection. Chronic histiocytic intervillositis may represent an idiosyncratic immune response, in this case to cytomegalovirus. Copyright © Informa Healthcare USA, Inc.
format Journal
author Taweevisit M.
Sukpan K.
Siriaunkgul S.
Thorner P.
spellingShingle Taweevisit M.
Sukpan K.
Siriaunkgul S.
Thorner P.
Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis
author_facet Taweevisit M.
Sukpan K.
Siriaunkgul S.
Thorner P.
author_sort Taweevisit M.
title Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis
title_short Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis
title_full Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis
title_fullStr Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis
title_full_unstemmed Chronic Histiocytic Intervillositis with Cytomegalovirus Placentitis in a Case of Hydrops Fetalis
title_sort chronic histiocytic intervillositis with cytomegalovirus placentitis in a case of hydrops fetalis
publishDate 2017
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84867703194&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/42720
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