Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men

• Main Authors: Anderson P., Glidden D., Liu A., Buchbinder S., Lama J., Guanira J., McMahan V., Bushman L., Casapía M., Montoya-Herrera O., Veloso V., Mayer K., Chariyalertsak S., Schechter M., Bekker L., Kallás E., Grant R.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866283847&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/42774
• Institution: Chiang Mai University

Drug concentrations associated with protection from HIV-1 acquisition have not been determined. We evaluated drug concentrations among men who have sex with men in a substudy of the iPrEx trial (1). In this randomized placebo-controlled trial, daily oral doses of emtricitabine/tenofovir disoproxil f...