A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry
© 2011 University of Istanbul. All rights reserved. A new isoflavone (1), along wilh daidzein (2), and genistin (3) were isolated from the Jacaranda oblusifolia twig extract. Their structures were elucidated by NMR and MS spectroscopy. Compound 1 possessed significant anticancer activity against KB...
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th-cmuir.6653943832-431372017-09-28T06:48:47Z A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry Khamsan S. Liawruangrath S. Tcerawutkulrag A. Pyne S. Garson M. Liawruangrath B. © 2011 University of Istanbul. All rights reserved. A new isoflavone (1), along wilh daidzein (2), and genistin (3) were isolated from the Jacaranda oblusifolia twig extract. Their structures were elucidated by NMR and MS spectroscopy. Compound 1 possessed significant anticancer activity against KB and NC1-H187 cell lines with the IC 50 values of 2.52 and 7.47 ng mL -1 , compound 2 and 3 exhibited anticancer activity against KB and NC1-HI87 cell lines wilh the IC 50 values of 5.73, 8.14, 2.83 and 27.30 μg mL -1 , respectively. Compound 2 also showed anticancer activity against MCF-7 cell line with an IC 50 value of 28.17 μg mL -1 . The isolates showed non-cytotoxic against Vero cells. 2017-09-28T06:48:47Z 2017-09-28T06:48:47Z 2011-01-01 Journal 13072080 2-s2.0-84863444888 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84863444888&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43137 |
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Chiang Mai University Library |
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Thailand |
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© 2011 University of Istanbul. All rights reserved. A new isoflavone (1), along wilh daidzein (2), and genistin (3) were isolated from the Jacaranda oblusifolia twig extract. Their structures were elucidated by NMR and MS spectroscopy. Compound 1 possessed significant anticancer activity against KB and NC1-H187 cell lines with the IC 50 values of 2.52 and 7.47 ng mL -1 , compound 2 and 3 exhibited anticancer activity against KB and NC1-HI87 cell lines wilh the IC 50 values of 5.73, 8.14, 2.83 and 27.30 μg mL -1 , respectively. Compound 2 also showed anticancer activity against MCF-7 cell line with an IC 50 value of 28.17 μg mL -1 . The isolates showed non-cytotoxic against Vero cells. |
| format |
Journal |
| author |
Khamsan S. Liawruangrath S. Tcerawutkulrag A. Pyne S. Garson M. Liawruangrath B. |
| spellingShingle |
Khamsan S. Liawruangrath S. Tcerawutkulrag A. Pyne S. Garson M. Liawruangrath B. A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry |
| author_facet |
Khamsan S. Liawruangrath S. Tcerawutkulrag A. Pyne S. Garson M. Liawruangrath B. |
| author_sort |
Khamsan S. |
| title |
A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry |
| title_short |
A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry |
| title_full |
A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry |
| title_fullStr |
A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry |
| title_full_unstemmed |
A new isoflavonc from Jacaranda obtusifolia H.B.K. ssp. rhombifolia (G.F.W. Meijer) gentry |
| title_sort |
new isoflavonc from jacaranda obtusifolia h.b.k. ssp. rhombifolia (g.f.w. meijer) gentry |
| publishDate |
2017 |
| url |
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84863444888&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43137 |
| _version_ |
1681422321712103424 |