Monitoring and impact of fluconazole serum and cerebrospinal fluid concentration in HIV-associated cryptococcal meningitis-infected patients

• Main Authors: Manosuthi W., Chetchotisakd P., Nolen T., Wallace D., Sungkanuparph S., Anekthananon T., Supparatpinyo K., Pappas P., Larsen R., Filler S., Andes D.
• Format: Journal
• Published: 2017
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950813660&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/43331
• Institution: Chiang Mai University

Objectives:The aim of the present study was to assess fluconazole pharmacokinetic measures in serum and cerebrospinal fluid (CSF); and the correlation of these measures with clinical outcomes of invasive fungal infections. Methods:A randomized trial was conduct ed in HIV-infected patients receiving...