Voltage-gated sodium channels assemble and gate as dimers

© 2017 The Author(s). Voltage-gated sodium channels are expressed in excitable tissues and mutations have been linked to cardiac arrhythmias and channelopathies. Here the authors show that the sodium channel α-subunits interact to form a dimer and gate as dimer and that this functional dimerisation...

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Main Authors:	Jérôme Clatot, Malcolm Hoshi, Xiaoping Wan, Haiyan Liu, Ankur Jain, Krekwit Shinlapawittayatorn, Céline Marionneau, Eckhard Ficker, Taekjip Ha, Isabelle Deschênes
Format:	Journal
Published:	2018
Subjects:	Biochemistry, Genetics and Molecular Biology Chemistry Agricultural and Biological Sciences Arts and Humanities
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037870387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43460
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-43460
record_format	dspace
spelling	th-cmuir.6653943832-434602018-04-25T07:35:32Z Voltage-gated sodium channels assemble and gate as dimers Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes Biochemistry, Genetics and Molecular Biology Chemistry Agricultural and Biological Sciences Arts and Humanities © 2017 The Author(s). Voltage-gated sodium channels are expressed in excitable tissues and mutations have been linked to cardiac arrhythmias and channelopathies. Here the authors show that the sodium channel α-subunits interact to form a dimer and gate as dimer and that this functional dimerisation is conserved. 2018-01-24T03:48:51Z 2018-01-24T03:48:51Z 2017-12-01 Journal 20411723 2-s2.0-85037870387 10.1038/s41467-017-02262-0 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037870387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43460
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Biochemistry, Genetics and Molecular Biology Chemistry Agricultural and Biological Sciences Arts and Humanities
spellingShingle	Biochemistry, Genetics and Molecular Biology Chemistry Agricultural and Biological Sciences Arts and Humanities Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes Voltage-gated sodium channels assemble and gate as dimers
description	© 2017 The Author(s). Voltage-gated sodium channels are expressed in excitable tissues and mutations have been linked to cardiac arrhythmias and channelopathies. Here the authors show that the sodium channel α-subunits interact to form a dimer and gate as dimer and that this functional dimerisation is conserved.
format	Journal
author	Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes
author_facet	Jérôme Clatot Malcolm Hoshi Xiaoping Wan Haiyan Liu Ankur Jain Krekwit Shinlapawittayatorn Céline Marionneau Eckhard Ficker Taekjip Ha Isabelle Deschênes
author_sort	Jérôme Clatot
title	Voltage-gated sodium channels assemble and gate as dimers
title_short	Voltage-gated sodium channels assemble and gate as dimers
title_full	Voltage-gated sodium channels assemble and gate as dimers
title_fullStr	Voltage-gated sodium channels assemble and gate as dimers
title_full_unstemmed	Voltage-gated sodium channels assemble and gate as dimers
title_sort	voltage-gated sodium channels assemble and gate as dimers
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037870387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43460
_version_	1681422377259368448

Voltage-gated sodium channels assemble and gate as dimers

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