Proficiency testing program for hemoglobin E, A<inf>2</inf>and F analysis in Thailand using lyophilized hemoglobin control materials

© 2017 Walter de Gruyter GmbH. There is no external quality assessment (EQA) program for hemoglobin analysis that uses lyophilized hemoglobin control materials with HbA 2 /E in levels as high as those found in people with the β-thalassemia trait, HbE trait, β-thalassemia/HbE disease or homozygous Hb...

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Main Authors: Sakorn Pornprasert, Monthathip Tookjai, Manoo Punyamung, Panida Pongpunyayuen, Kallayanee Treesuwan
Format: Book
Published: 2018
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037819147&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/43469
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-434692018-01-24T03:49:00Z Proficiency testing program for hemoglobin E, A<inf>2</inf>and F analysis in Thailand using lyophilized hemoglobin control materials Sakorn Pornprasert Monthathip Tookjai Manoo Punyamung Panida Pongpunyayuen Kallayanee Treesuwan © 2017 Walter de Gruyter GmbH. There is no external quality assessment (EQA) program for hemoglobin analysis that uses lyophilized hemoglobin control materials with HbA 2 /E in levels as high as those found in people with the β-thalassemia trait, HbE trait, β-thalassemia/HbE disease or homozygous HbE; these are all found frequently in the southeast Asian population. The aim of this study was to evaluate the efficiency of the control materials used in the established proficiency testing (PT) program at the Associated Medical Sciences-Clinical Service Center (AMC-CSC), Chiang Mai University, Chiang Mai, Thailand. The PT program for Hb analysis and the thalassemia interpretation was established in compliance with ISO/IEC17043:2010. Three cycles per year were performed in 2015 and 2016. In each cycle, three different types of control material were provided to the participants. Each participant analyzed the control materials in the same manner as in their routine practices. Hb analysis results and their thalassemia interpretation codes were entered into the report form and sent back to AMC-CSC. The number of participants increased from 63 in 2015 to 76 in 2016. In addition, the number of participants who took part in all three cycles increased from 95.2% (60/63) in 2015 to 100% (76/76) in 2016. All participants reported the correct Hb measurement and type; however, misinterpretations in thalassemia diagnosis were noted. The lyophilized hemoglobin control materials prepared at AMC-CSC were used successfully in our PT program. However, the study results indicate the need for further improvement in thalassemia interpretation skills for laboratory staff. 2018-01-24T03:49:00Z 2018-01-24T03:49:00Z 2017-11-25 Book 14374331 14346621 2-s2.0-85037819147 10.1515/cclm-2017-0581 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037819147&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43469
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description © 2017 Walter de Gruyter GmbH. There is no external quality assessment (EQA) program for hemoglobin analysis that uses lyophilized hemoglobin control materials with HbA 2 /E in levels as high as those found in people with the β-thalassemia trait, HbE trait, β-thalassemia/HbE disease or homozygous HbE; these are all found frequently in the southeast Asian population. The aim of this study was to evaluate the efficiency of the control materials used in the established proficiency testing (PT) program at the Associated Medical Sciences-Clinical Service Center (AMC-CSC), Chiang Mai University, Chiang Mai, Thailand. The PT program for Hb analysis and the thalassemia interpretation was established in compliance with ISO/IEC17043:2010. Three cycles per year were performed in 2015 and 2016. In each cycle, three different types of control material were provided to the participants. Each participant analyzed the control materials in the same manner as in their routine practices. Hb analysis results and their thalassemia interpretation codes were entered into the report form and sent back to AMC-CSC. The number of participants increased from 63 in 2015 to 76 in 2016. In addition, the number of participants who took part in all three cycles increased from 95.2% (60/63) in 2015 to 100% (76/76) in 2016. All participants reported the correct Hb measurement and type; however, misinterpretations in thalassemia diagnosis were noted. The lyophilized hemoglobin control materials prepared at AMC-CSC were used successfully in our PT program. However, the study results indicate the need for further improvement in thalassemia interpretation skills for laboratory staff.
format Book
author Sakorn Pornprasert
Monthathip Tookjai
Manoo Punyamung
Panida Pongpunyayuen
Kallayanee Treesuwan
spellingShingle Sakorn Pornprasert
Monthathip Tookjai
Manoo Punyamung
Panida Pongpunyayuen
Kallayanee Treesuwan
Proficiency testing program for hemoglobin E, A<inf>2</inf>and F analysis in Thailand using lyophilized hemoglobin control materials
author_facet Sakorn Pornprasert
Monthathip Tookjai
Manoo Punyamung
Panida Pongpunyayuen
Kallayanee Treesuwan
author_sort Sakorn Pornprasert
title Proficiency testing program for hemoglobin E, A<inf>2</inf>and F analysis in Thailand using lyophilized hemoglobin control materials
title_short Proficiency testing program for hemoglobin E, A<inf>2</inf>and F analysis in Thailand using lyophilized hemoglobin control materials
title_full Proficiency testing program for hemoglobin E, A<inf>2</inf>and F analysis in Thailand using lyophilized hemoglobin control materials
title_fullStr Proficiency testing program for hemoglobin E, A<inf>2</inf>and F analysis in Thailand using lyophilized hemoglobin control materials
title_full_unstemmed Proficiency testing program for hemoglobin E, A<inf>2</inf>and F analysis in Thailand using lyophilized hemoglobin control materials
title_sort proficiency testing program for hemoglobin e, a<inf>2</inf>and f analysis in thailand using lyophilized hemoglobin control materials
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85037819147&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/43469
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