Pharmacogenetics-based population pharmacokinetic analysis of tenofovir in Thai HIV-infected patients

Pharmacogenetics-based population pharmacokinetic analysis of tenofovir in Thai HIV-infected patients

© 2017 Future Medicine Ltd. Aim: To develop a population pharmacokinetic model and identify sources of variability, genetic and nongenetic factors, of tenofovir. Methods: The ABCC2 and ABCC4 polymorphisms were genotyped in 342 patients. A nonlinear mixed effects model was used to develop the populat...

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Main Authors: Kanokrat Rungtivasuwan, Anchalee Avihingsanon, Narukjaporn Thammajaruk, Siwaporn Mitruk, David M. Burger, Kiat Ruxrungtham, Chonlaphat Sukasem, Baralee Punyawudho
Format: Journal
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Agricultural and Biological Sciences
Arts and Humanities
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85034419484&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/43530
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Institution: Chiang Mai University

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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85034419484&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/43530

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