Molecular modeling elucidates the cellular mechanism of synaptotagmin-SNARE inhibition: a novel plausible route to anti-wrinkle activity of botox-like cosmetic active molecules

• Main Authors: Pathomwat Wongrattanakamon, Piyarat Nimmanpipug, Busaban Sirithunyalug, Supat Jiranusornkul
• 格式: 雜誌
• 出版: 2018
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85030865999&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/43581
• 機構: Chiang Mai University

© 2017 Springer Science+Business Media, LLC Synaptotagmin 1 (Syt1) is the Ca 2+ sensor protein with an essential role in neurotransmitter release. Since the wrinkle formation is due to the excessive muscle fiber stimulation in the face, a helpful stratagem to diminish the wrinkle line intenseness is...