Molecular modeling elucidates the cellular mechanism of synaptotagmin-SNARE inhibition: a novel plausible route to anti-wrinkle activity of botox-like cosmetic active molecules

© 2017, Springer Science+Business Media, LLC. Synaptotagmin 1 (Syt1) is the Ca2+sensor protein with an essential role in neurotransmitter release. Since the wrinkle formation is due to the excessive muscle fiber stimulation in the face, a helpful stratagem to diminish the wrinkle line intenseness is...

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Bibliographic Details
Main Authors: Pathomwat Wongrattanakamon, Piyarat Nimmanpipug, Busaban Sirithunyalug, Supat Jiranusornkul
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85030865999&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/58249
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Institution: Chiang Mai University