A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media

© 2015 Elsevier Ltd. All rights reserved. A convenient one-pot, two-step procedure for the synthesis of ketone cyanohydrin esters in aqueous media is reported using N-acylbenzotriazoles as the acylating agents. In saturated aqueous sodium bicarbonate containing a catalytic amount of tetrabutylammoni...

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Main Authors:	Sirawit Wet-Osot, Mookda Pattarawarapan, Wong Phakhodee
Format:	Journal
Published:	2018
Subjects:	Agricultural and Biological Sciences
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84949106013&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43954
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-43954
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spelling	th-cmuir.6653943832-439542018-04-25T07:44:09Z A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media Sirawit Wet-Osot Mookda Pattarawarapan Wong Phakhodee Agricultural and Biological Sciences © 2015 Elsevier Ltd. All rights reserved. A convenient one-pot, two-step procedure for the synthesis of ketone cyanohydrin esters in aqueous media is reported using N-acylbenzotriazoles as the acylating agents. In saturated aqueous sodium bicarbonate containing a catalytic amount of tetrabutylammonium bromide, the reaction of ketones with potassium cyanide and N-acylbenzotriazoles proceeded readily at room temperature to provide the corresponding O-acyl cyanohydrin derivatives in good to excellent yields. 2018-01-24T04:36:27Z 2018-01-24T04:36:27Z 2015-12-30 Journal 18733581 00404039 2-s2.0-84949106013 10.1016/j.tetlet.2015.11.038 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84949106013&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43954
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
topic	Agricultural and Biological Sciences
spellingShingle	Agricultural and Biological Sciences Sirawit Wet-Osot Mookda Pattarawarapan Wong Phakhodee A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media
description	© 2015 Elsevier Ltd. All rights reserved. A convenient one-pot, two-step procedure for the synthesis of ketone cyanohydrin esters in aqueous media is reported using N-acylbenzotriazoles as the acylating agents. In saturated aqueous sodium bicarbonate containing a catalytic amount of tetrabutylammonium bromide, the reaction of ketones with potassium cyanide and N-acylbenzotriazoles proceeded readily at room temperature to provide the corresponding O-acyl cyanohydrin derivatives in good to excellent yields.
format	Journal
author	Sirawit Wet-Osot Mookda Pattarawarapan Wong Phakhodee
author_facet	Sirawit Wet-Osot Mookda Pattarawarapan Wong Phakhodee
author_sort	Sirawit Wet-Osot
title	A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media
title_short	A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media
title_full	A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media
title_fullStr	A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media
title_full_unstemmed	A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media
title_sort	convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84949106013&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43954
_version_	1681422469581242368

A convenient one-pot synthesis of ketone cyanohydrin esters in aqueous media

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