TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media
© 2015 Elsevier Ltd. All rights reserved. The synthesis of N-acylbenzotriazoles has been demonstrated by the 2,4,6-trichloro-1,3,5-triazine (TCT)-mediated condensation of carboxylic acids with 1H-benzotriazole in aqueous media. In saturated aqueous sodium bicarbonate, TCT was found to be relatively...
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th-cmuir.6653943832-439692018-04-25T07:44:13Z TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media Sirawit Wet-Osot Wong Phakhodee Mookda Pattarawarapan Agricultural and Biological Sciences © 2015 Elsevier Ltd. All rights reserved. The synthesis of N-acylbenzotriazoles has been demonstrated by the 2,4,6-trichloro-1,3,5-triazine (TCT)-mediated condensation of carboxylic acids with 1H-benzotriazole in aqueous media. In saturated aqueous sodium bicarbonate, TCT was found to be relatively stable and functioned as an efficient acid activator in the acyl transfer process. This operationally simple and economic method allows the scalable synthesis of N-acylbenzotriazoles in good to excellent yields. 2018-01-24T04:36:35Z 2018-01-24T04:36:35Z 2015-12-16 Journal 18733581 00404039 2-s2.0-84947599657 10.1016/j.tetlet.2015.10.109 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84947599657&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43969 |
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Agricultural and Biological Sciences Sirawit Wet-Osot Wong Phakhodee Mookda Pattarawarapan TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media |
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© 2015 Elsevier Ltd. All rights reserved. The synthesis of N-acylbenzotriazoles has been demonstrated by the 2,4,6-trichloro-1,3,5-triazine (TCT)-mediated condensation of carboxylic acids with 1H-benzotriazole in aqueous media. In saturated aqueous sodium bicarbonate, TCT was found to be relatively stable and functioned as an efficient acid activator in the acyl transfer process. This operationally simple and economic method allows the scalable synthesis of N-acylbenzotriazoles in good to excellent yields. |
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Sirawit Wet-Osot Wong Phakhodee Mookda Pattarawarapan |
author_facet |
Sirawit Wet-Osot Wong Phakhodee Mookda Pattarawarapan |
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Sirawit Wet-Osot |
title |
TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media |
title_short |
TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media |
title_full |
TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media |
title_fullStr |
TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media |
title_full_unstemmed |
TCT-mediated synthesis of N-acylbenzotriazoles in aqueous media |
title_sort |
tct-mediated synthesis of n-acylbenzotriazoles in aqueous media |
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2018 |
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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84947599657&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/43969 |
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