Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases

© 2015 Pothirat et al. Background: Chronic obstructive pulmonary disease (COPD) and other chronic respiratory diseases (CRDs) have significant impacts on quality of life including psychomotor domain. Purpose: To evaluate three major affective disorders in subjects with COPD compared with other CRDs...

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Main Authors: Chaicharn Pothirat, Warawut Chaiwong, Nittaya Phetsuk, Sangnual Pisalthanapuna, Nonglak Chetsadaphan, Juthamas Inchai
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/44250
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-442502018-04-25T07:47:25Z Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases Chaicharn Pothirat Warawut Chaiwong Nittaya Phetsuk Sangnual Pisalthanapuna Nonglak Chetsadaphan Juthamas Inchai Agricultural and Biological Sciences © 2015 Pothirat et al. Background: Chronic obstructive pulmonary disease (COPD) and other chronic respiratory diseases (CRDs) have significant impacts on quality of life including psychomotor domain. Purpose: To evaluate three major affective disorders in subjects with COPD compared with other CRDs and nonill population. Materials and methods: The Thai version of Mini International Neuropsychiatric Interview (MINI) was used as a diagnostic instrument for three major affective disorders (generalized anxiety disorder, major depressive disorder, and panic disorder) by face-to-face interview in assessing patients with CRDs [COPD, asthma, rhinasthma, all asthma (asthma and rhinasthma), and chronic rhinitis], and nonill subjects. Logistic regression analyses were used to determine the relation between major affective disorders and CRDs adjusting for age, sex, and disease severity. Results: Major affective disorders were more prevalent in CRDs than nonill groups (adjusted OR =2.6 [95% CI, 1.8−3.9] , P < 0.001). COPD patients had significantly more generalized anxiety and panic disorder (adjusted OR =4.0 [95% CI, 1.4−11.9], P=0.011, and 4.4 [95% CI, 1.1−18.1] , P=0.038, respectively) but not major depressive disorder (adjusted OR =2.7 [95% CI, 0.8−9.0, P=0.105]) than nonill group. Comparing with all asthma, COPD patients had lower occurrence of major depressive and panic disorders (adjusted OR =0.1 [95% CI, 0.0−0.4] , P=0.002, and 0.1 [95% CI, 0.0−0.9], P=0.043, respectively). There was no difference in major mood disorders in COPD, rhinasthma, and chronic rhinitis patients. Major affective disorders were not increased by disease severity in COPD. Conclusion: Major affective disorders were significantly higher in CRDs than nonill population. Generalized anxiety and panic disorders were significantly high in COPD patients. Moreover, major depressive and panic disorders in COPD were significantly lower than all asthma. The prevalence of major affective disorders may not be related to severity of COPD. 2018-01-24T04:39:55Z 2018-01-24T04:39:55Z 2015-08-07 Journal 11782005 11769106 2-s2.0-84939232197 10.2147/COPD.S86742 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84939232197&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/44250
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Agricultural and Biological Sciences
spellingShingle Agricultural and Biological Sciences
Chaicharn Pothirat
Warawut Chaiwong
Nittaya Phetsuk
Sangnual Pisalthanapuna
Nonglak Chetsadaphan
Juthamas Inchai
Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases
description © 2015 Pothirat et al. Background: Chronic obstructive pulmonary disease (COPD) and other chronic respiratory diseases (CRDs) have significant impacts on quality of life including psychomotor domain. Purpose: To evaluate three major affective disorders in subjects with COPD compared with other CRDs and nonill population. Materials and methods: The Thai version of Mini International Neuropsychiatric Interview (MINI) was used as a diagnostic instrument for three major affective disorders (generalized anxiety disorder, major depressive disorder, and panic disorder) by face-to-face interview in assessing patients with CRDs [COPD, asthma, rhinasthma, all asthma (asthma and rhinasthma), and chronic rhinitis], and nonill subjects. Logistic regression analyses were used to determine the relation between major affective disorders and CRDs adjusting for age, sex, and disease severity. Results: Major affective disorders were more prevalent in CRDs than nonill groups (adjusted OR =2.6 [95% CI, 1.8−3.9] , P < 0.001). COPD patients had significantly more generalized anxiety and panic disorder (adjusted OR =4.0 [95% CI, 1.4−11.9], P=0.011, and 4.4 [95% CI, 1.1−18.1] , P=0.038, respectively) but not major depressive disorder (adjusted OR =2.7 [95% CI, 0.8−9.0, P=0.105]) than nonill group. Comparing with all asthma, COPD patients had lower occurrence of major depressive and panic disorders (adjusted OR =0.1 [95% CI, 0.0−0.4] , P=0.002, and 0.1 [95% CI, 0.0−0.9], P=0.043, respectively). There was no difference in major mood disorders in COPD, rhinasthma, and chronic rhinitis patients. Major affective disorders were not increased by disease severity in COPD. Conclusion: Major affective disorders were significantly higher in CRDs than nonill population. Generalized anxiety and panic disorders were significantly high in COPD patients. Moreover, major depressive and panic disorders in COPD were significantly lower than all asthma. The prevalence of major affective disorders may not be related to severity of COPD.
format Journal
author Chaicharn Pothirat
Warawut Chaiwong
Nittaya Phetsuk
Sangnual Pisalthanapuna
Nonglak Chetsadaphan
Juthamas Inchai
author_facet Chaicharn Pothirat
Warawut Chaiwong
Nittaya Phetsuk
Sangnual Pisalthanapuna
Nonglak Chetsadaphan
Juthamas Inchai
author_sort Chaicharn Pothirat
title Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases
title_short Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases
title_full Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases
title_fullStr Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases
title_full_unstemmed Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases
title_sort major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84939232197&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/44250
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