Biological activity of dolichandrone serrulata flowers and their active components

Dolichandrone serrulata (DC.) Seem flowers are widely used as vegetables in northern and eastern Thailand. Biological studies of the methanolic extract of these flowers have shown promising antioxidant activity. Biological-guided separation of D. serrulata flowers yielded six compounds, identified a...

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Main Authors: Phanida Phanthong, Noppawan Phumala Morales, Sirirat Chancharunee, Supachoke Mangmool, Natthinee Anantachoke, Nuntavan Bunyapraphatsara
Format: Journal
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/44718
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-447182018-04-25T07:54:58Z Biological activity of dolichandrone serrulata flowers and their active components Phanida Phanthong Noppawan Phumala Morales Sirirat Chancharunee Supachoke Mangmool Natthinee Anantachoke Nuntavan Bunyapraphatsara Agricultural and Biological Sciences Dolichandrone serrulata (DC.) Seem flowers are widely used as vegetables in northern and eastern Thailand. Biological studies of the methanolic extract of these flowers have shown promising antioxidant activity. Biological-guided separation of D. serrulata flowers yielded six compounds, identified as hallerone, protocatechuic acid, rengyolone, cleroindicin B, ixoside, and isomaltose. This is the first report on hallerone, protocatechuic acid, rengyolone, cleroindicin B, and isomaltose in D. serrulata. Protocatechuic acid was the most potent scavenger of 2,2-diphenyl-l-picrylhydrazyl and hydroxyl radicals with IC 50 values of 25.6 ± 0.6 and 29.6 ± 0.4 μM, respectively. Hallerone and rengyolone showed moderate scavenging action on superoxide radicals and inhibited H 2 O 2 induced reactive oxygen species production in HEK-293 cell. In addition, the other isolated compounds showed weak activity. 2018-01-24T04:47:02Z 2018-01-24T04:47:02Z 2015-01-01 Journal 15559475 1934578X 2-s2.0-84945995793 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84945995793&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/44718
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Agricultural and Biological Sciences
spellingShingle Agricultural and Biological Sciences
Phanida Phanthong
Noppawan Phumala Morales
Sirirat Chancharunee
Supachoke Mangmool
Natthinee Anantachoke
Nuntavan Bunyapraphatsara
Biological activity of dolichandrone serrulata flowers and their active components
description Dolichandrone serrulata (DC.) Seem flowers are widely used as vegetables in northern and eastern Thailand. Biological studies of the methanolic extract of these flowers have shown promising antioxidant activity. Biological-guided separation of D. serrulata flowers yielded six compounds, identified as hallerone, protocatechuic acid, rengyolone, cleroindicin B, ixoside, and isomaltose. This is the first report on hallerone, protocatechuic acid, rengyolone, cleroindicin B, and isomaltose in D. serrulata. Protocatechuic acid was the most potent scavenger of 2,2-diphenyl-l-picrylhydrazyl and hydroxyl radicals with IC 50 values of 25.6 ± 0.6 and 29.6 ± 0.4 μM, respectively. Hallerone and rengyolone showed moderate scavenging action on superoxide radicals and inhibited H 2 O 2 induced reactive oxygen species production in HEK-293 cell. In addition, the other isolated compounds showed weak activity.
format Journal
author Phanida Phanthong
Noppawan Phumala Morales
Sirirat Chancharunee
Supachoke Mangmool
Natthinee Anantachoke
Nuntavan Bunyapraphatsara
author_facet Phanida Phanthong
Noppawan Phumala Morales
Sirirat Chancharunee
Supachoke Mangmool
Natthinee Anantachoke
Nuntavan Bunyapraphatsara
author_sort Phanida Phanthong
title Biological activity of dolichandrone serrulata flowers and their active components
title_short Biological activity of dolichandrone serrulata flowers and their active components
title_full Biological activity of dolichandrone serrulata flowers and their active components
title_fullStr Biological activity of dolichandrone serrulata flowers and their active components
title_full_unstemmed Biological activity of dolichandrone serrulata flowers and their active components
title_sort biological activity of dolichandrone serrulata flowers and their active components
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84945995793&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/44718
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