International multi-institutional bench mark study on dosimetric and volumetric modulation using helical tomotherapy treatment planning for malignant pleural mesothelioma tumors

• Main Authors: Allen Movahed, Tommy Knöös, Claire Foottit, André Haraldsson, Dirk Verellen, Koen Tournel, Sharon Qi, Dale Matson, Thuy Lau, Milton Vargas, Somsak Wanwilairat, Christine Higby, Osama Hassad, Belal Moftah, Thomas Lacornerie, Antoine Wagner, Hew Choon Soong
• 格式: Conference Proceeding
• 出版: 2018
• 主題: Agricultural and Biological Sciences
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84944327994&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/44908

© Springer International Publishing Switzerland 2015. Determining the most desirable and achievable target dose and organ at risk (OAR) sparing using helical TomoTherapy planning system for mesothelioma treatment plans. A range of planning parameters was used. The reviewers’ ranking assessment (Ranking in Groups: 1 = Good, 2 = Above Average, 3 = Average, 4 = Poor).The overall rankings revealed that a plan with a balanced tradeoff among all planning objectives was preferred by most participants and reviewers. Other studies found low doses to the contralateral lung to be limiting. This was not the case in our study, with TomoTherapy we found the dose to contra lateral lung to be as low as V5Gy=0.87%. A pitch value of 0.287 or 0.43 would provide better result. A delivered modulation factor of above 1.7 and a treatment time around 500 sec will be beneficial consideration in planning.