Enhancement of transdermal absorption, gene expression and stability of tyrosinase plasmid (pMEL34)-loaded elastic cationic niosomes: Potential application in vitiligo treatment

Enhancement of transdermal absorption, gene expression and stability of tyrosinase plasmid (pMEL34)-loaded elastic cationic niosomes: Potential application in vitiligo treatment

The pMEL34 was loaded in elastic cationic niosomes (Tween61/Cholesterol/ DDAB at 1:1:0.5 molar ratio) by chloroform film method with sonication and rehydrated with 25% ethanol. The amount of pMEL34 was determined by gel electrophoresis and gel documentation. The maximum loading of pMEL34 in elastic...

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Bibliographic Details
Main Authors: Manosroi J., Khositsuntiwong N., Manosroi W., Gotz F., Werner R.G., Manosroi A.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-77955109408&partnerID=40&md5=a747fa753e2980ef32d02a38df701938
http://www.ncbi.nlm.nih.gov/pubmed/20213835
http://cmuir.cmu.ac.th/handle/6653943832/4494
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Institution: Chiang Mai University
Language: English

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http://www.scopus.com/inward/record.url?eid=2-s2.0-77955109408&partnerID=40&md5=a747fa753e2980ef32d02a38df701938
http://www.ncbi.nlm.nih.gov/pubmed/20213835
http://cmuir.cmu.ac.th/handle/6653943832/4494

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