Induction of neutralizing antibody response against four dengue viruses in mice by intramuscular electroporation of tetravalent DNA vaccines

• Main Authors: Eakachai Prompetchara, Chutitorn Ketloy, Poonsook Keelapang, Nopporn Sittisombut, Kiat Ruxrungtham
• Format: Journal
• Published: 2018
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84902336223&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/45041
• Institution: Chiang Mai University

DNA vaccine against dengue is an interesting strategy for a prime/boost approach. This study evaluated neutralizing antibody (NAb) induction of a dengue tetravalent DNA (TDNA) vaccine candidate administered by intramuscular- electroporation (IM-EP) and the benefit of homologous TDNA boosting in mice...