Impaired insulin signaling affects renal organic anion transporter 3 (Oat3) function in streptozotocin-induced diabetic rats

• المؤلفون الرئيسيون: Anusorn Lungkaphin, Phatchawan Arjinajarn, Anchalee Pongchaidecha, Chutima Srimaroeng, Lisa Chatsudthipong, Varanuj Chatsudthipong
• التنسيق: دورية
• منشور في: 2018
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84900441583&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/45053

Organic anion transporter 3 (Oat3) is a major renal Oats expressed in the basolateral membrane of renal proximal tubule cells. We have recently reported decreases in renal Oat3 function and expression in diabetic rats and these changes were recovered after insulin treatment for four weeks. However,...