PEG-OCL micelles for quercetin solubilization and inhibition of cancer cell growth

• المؤلفون الرئيسيون: Khonkarn R., Mankhetkorn S., Hennink W.E., Okonogi S.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-80054974549&partnerID=40&md5=a1cbd6a37a987c8f370186de56d0cba6; http://www.ncbi.nlm.nih.gov/pubmed/21596135; http://cmuir.cmu.ac.th/handle/6653943832/4512

In this study, quercetin (QCT), a flavonoid with high anticancer potential, was loaded into polymeric micelles of PEG-OCL (poly(ethylene glycol)-b-oligo(e-caprolactone)) with naphthyl or benzyl end groups in order to increase its aqueous solubility. The cytostatic activity of the QCT-loaded micelles...