Potency of extemporaneous gentamicin eye drops used in maharaj nakorn chiang mai hospital
This study evaluated the potency of extemporaneous gentamicin (13.6 mg/ml) eye drops, stored for 4 weeks. The effects of different storage temperatures on the antimibrobial potency were examined. Gentamicin (13.6 mg/ml) was prepared with aseptic technique and the solutions stored at 2-8°C and 28°C f...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-77953805162&partnerID=40&md5=0f0f4003f1b1a1f4a6ce3b9505e95162 http://cmuir.cmu.ac.th/handle/6653943832/4538 |
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| Institution: | Chiang Mai University |
| Language: | English |
| Summary: | This study evaluated the potency of extemporaneous gentamicin (13.6 mg/ml) eye drops, stored for 4 weeks. The effects of different storage temperatures on the antimibrobial potency were examined. Gentamicin (13.6 mg/ml) was prepared with aseptic technique and the solutions stored at 2-8°C and 28°C for 28 days. The fortified stock solutions of gentamicin (13.6 mg/ml) were prepared by reconstituting gentamicin (0.3%) eye drops with gentamicin (40 mg/ml) injection. The potency was evaluated by measuring the minimum inhibitory concentration. Throughout the 28-day period, no change was observed in the minimum inhibitory concentration of gentamicin (13.6 mg/ml) stored at 2-8°C and 28°C. Extemporaneously - prepared gentamicin (13.6 mg/ml) eye drops remained stable at 2-8°C and 28°C for 28 days. |
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