Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand

Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand

Four Combretum species (Combretaceae) from northern Thailand (Combretum deciduum, Combretum griffithii, Combretum latifolium and Combretum quadrangulare) were tested for antioxidant and anticancer activities. Antioxidant activities were assessed by ABTS and DPPH radical scavenging capacity methods....

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Main Authors: Wimaluk Nopsiri, Sunee Chansakaow, Somporn Putiyanan, Surapol Natakankitkul, Dammrong Santiarworn
Format: Journal
Published: 2018
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84902328073&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/45421
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Institution: Chiang Mai University
id th-cmuir.6653943832-45421
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spelling th-cmuir.6653943832-454212018-01-24T06:10:10Z Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand Wimaluk Nopsiri Sunee Chansakaow Somporn Putiyanan Surapol Natakankitkul Dammrong Santiarworn Four Combretum species (Combretaceae) from northern Thailand (Combretum deciduum, Combretum griffithii, Combretum latifolium and Combretum quadrangulare) were tested for antioxidant and anticancer activities. Antioxidant activities were assessed by ABTS and DPPH radical scavenging capacity methods. Anticancer activity was tested against three cancerous human cell lines (KB, MCF7 and NCI-H187). All methanolic leaf extracts showed antioxidant activities with the ABTS and DPPH methods. The methanolic leaf extracts of C. deciduum inhibited KB-oral cavity and MCF7-breast cancer cell lines, C. latifolium inhibited MCF7-breast cancer cell line and C. quadrangulare inhibited KB-oral cavity and NCI-H187-small cell lung cancer cell lines. However, the methanolic leaf extracts of C. griffithii were inactive against all three cell lines. All methanolic leaf extracts exhibited non-cytotoxicity to Vero cell lines. 2018-01-24T06:10:10Z 2018-01-24T06:10:10Z 2014-01-01 Journal 16851994 2-s2.0-84902328073 10.12982/CMUJNS.2014.0031 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84902328073&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/45421
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description Four Combretum species (Combretaceae) from northern Thailand (Combretum deciduum, Combretum griffithii, Combretum latifolium and Combretum quadrangulare) were tested for antioxidant and anticancer activities. Antioxidant activities were assessed by ABTS and DPPH radical scavenging capacity methods. Anticancer activity was tested against three cancerous human cell lines (KB, MCF7 and NCI-H187). All methanolic leaf extracts showed antioxidant activities with the ABTS and DPPH methods. The methanolic leaf extracts of C. deciduum inhibited KB-oral cavity and MCF7-breast cancer cell lines, C. latifolium inhibited MCF7-breast cancer cell line and C. quadrangulare inhibited KB-oral cavity and NCI-H187-small cell lung cancer cell lines. However, the methanolic leaf extracts of C. griffithii were inactive against all three cell lines. All methanolic leaf extracts exhibited non-cytotoxicity to Vero cell lines.
format Journal
author Wimaluk Nopsiri
Sunee Chansakaow
Somporn Putiyanan
Surapol Natakankitkul
Dammrong Santiarworn
spellingShingle Wimaluk Nopsiri
Sunee Chansakaow
Somporn Putiyanan
Surapol Natakankitkul
Dammrong Santiarworn
Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand
author_facet Wimaluk Nopsiri
Sunee Chansakaow
Somporn Putiyanan
Surapol Natakankitkul
Dammrong Santiarworn
author_sort Wimaluk Nopsiri
title Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand
title_short Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand
title_full Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand
title_fullStr Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand
title_full_unstemmed Antioxidant and anticancer activities from leaf extracts of four Combretum species from Northern Thailand
title_sort antioxidant and anticancer activities from leaf extracts of four combretum species from northern thailand
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84902328073&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/45421
_version_ 1681422742222536704

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