The treatment outcome of radical radiotherapy in laryngeal cancer

• Main Authors: Imjai Chitapanarux, Ekkasit Tharavichitkul, Somvilai Chakrabandhu, Pitchayaponne Klunklin, Wimrak Onchan, Nantaka Pukanhapan, Jirawattana Srikawin, Pichit Sittitrai, Roy Vongtama
• Format: Journal
• Published: 2018
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84899437548&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/45490
• Institution: Chiang Mai University

Objective: This study reports the treatment outcome of radiotherapy alone for laryngeal cancer. Material and Method: A retrospective analysis was performed on 138 patients with stage I to IV squamous cell carcinoma of larynx who received radiotherapy alone in Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Thailand between 2003 and 2009. Results: The 4-year local control (LC) rate in all patients was 44.1%. The 4-year overall survival (OS) was 82.1%. The 4-year LC rates for stage I, II, III, and IV were 75.3%, 69.4%, 57.1%, and 36.9%,respectively (p = 0.0055). Finally, the 4-year OS rates for stage I, II, III, and IV were 85%, 78.6%, 91.1%, and 71.5%, respectively. The laryngeal preservation rate of all stages was 73%. Conclusion: In conclusion, the treatment outcome of radiotherapy alone in all stages of laryngeal cancer in our center was unsatisfactory when compared to other series.