Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa

Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa

A phytochemical investigation of the acetone extract from the immature fruits of Garcinia cowa led to the isolation of two novel tetraoxygenated xanthones, garcicowanones A (1) and B (2), together with eight known tetraoxygeanted xanthones. Their structures were determined by spectroscopic analysis....

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Main Authors: Chiramet Auranwiwat, Kongkiat Trisuwan, Aroonchai Saiai, Stephen G. Pyne, Thunwadee Ritthiwigrom
Format: Journal
Published: 2018
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84907346833&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/45572
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-455722018-01-24T06:12:27Z Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa Chiramet Auranwiwat Kongkiat Trisuwan Aroonchai Saiai Stephen G. Pyne Thunwadee Ritthiwigrom A phytochemical investigation of the acetone extract from the immature fruits of Garcinia cowa led to the isolation of two novel tetraoxygenated xanthones, garcicowanones A (1) and B (2), together with eight known tetraoxygeanted xanthones. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their antibacterial activity against Bacillus cereus TISTR 688, Bacillus subtilis TISTR 008, Micrococcus luteus TISTR 884, Staphylococcus aureus TISTR 1466, Escherichia coli TISTR 780, Pseudomonas aeruginosa TISTR 781, Salmonella typhimurium TISTR 292 and Staphylococcus epidermidis ATCC 12228. α-Mangostin showed potent activity (MIC 0.25-1 μg/mL) against three Gram-positive strains and garcicowanone A and β-mangostin exhibited strong antibacterial activity against B. cereus with the same MIC values of 0.25 μg/mL. © 2014 Elsevier B.V. All rights reserved. 2018-01-24T06:12:27Z 2018-01-24T06:12:27Z 2014-01-01 Journal 18736971 0367326X 2-s2.0-84907346833 10.1016/j.fitote.2014.08.003 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84907346833&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/45572
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description A phytochemical investigation of the acetone extract from the immature fruits of Garcinia cowa led to the isolation of two novel tetraoxygenated xanthones, garcicowanones A (1) and B (2), together with eight known tetraoxygeanted xanthones. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their antibacterial activity against Bacillus cereus TISTR 688, Bacillus subtilis TISTR 008, Micrococcus luteus TISTR 884, Staphylococcus aureus TISTR 1466, Escherichia coli TISTR 780, Pseudomonas aeruginosa TISTR 781, Salmonella typhimurium TISTR 292 and Staphylococcus epidermidis ATCC 12228. α-Mangostin showed potent activity (MIC 0.25-1 μg/mL) against three Gram-positive strains and garcicowanone A and β-mangostin exhibited strong antibacterial activity against B. cereus with the same MIC values of 0.25 μg/mL. © 2014 Elsevier B.V. All rights reserved.
format Journal
author Chiramet Auranwiwat
Kongkiat Trisuwan
Aroonchai Saiai
Stephen G. Pyne
Thunwadee Ritthiwigrom
spellingShingle Chiramet Auranwiwat
Kongkiat Trisuwan
Aroonchai Saiai
Stephen G. Pyne
Thunwadee Ritthiwigrom
Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
author_facet Chiramet Auranwiwat
Kongkiat Trisuwan
Aroonchai Saiai
Stephen G. Pyne
Thunwadee Ritthiwigrom
author_sort Chiramet Auranwiwat
title Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_short Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_full Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_fullStr Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_full_unstemmed Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa
title_sort antibacterial tetraoxygenated xanthones from the immature fruits of garcinia cowa
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84907346833&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/45572
_version_ 1681422770433425408

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