Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)

Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)

The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nig...

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Main Authors: Ittipon Siridechakorn, Wisanu Maneerat, Tawanun Sripisut, Thunwadee Ritthiwigrom, Sarot Cheenpracha, Surat Laphookhieo
Format: Journal
Published: 2018
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84896311465&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/45722
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-457222018-01-24T06:16:21Z Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae) Ittipon Siridechakorn Wisanu Maneerat Tawanun Sripisut Thunwadee Ritthiwigrom Sarot Cheenpracha Surat Laphookhieo The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nigrolineabiphenyl B (4); and four xanthones, 1,3,6-trihydroxy-8-isoprenyl-7- methoxyxanthone (5), morusignin K (6), 1,5-dihydroxyxanthone (7), and 1,7-dihydroxyxanthone (8), were isolated from the acetone extract of the twigs of a Garcinia sp. Their structures were characterized extensively by 1D and 2D NMR spectroscopy and HR-EI-MS. The cytotoxicity of the two new biphenyls against the oral cavity cancer (KB) and the breast cancer (MCF7) cell lines was also evaluated. © 2014 Phytochemical Society of Europe. 2018-01-24T06:16:21Z 2018-01-24T06:16:21Z 2014-01-01 Journal 18767486 18743900 2-s2.0-84896311465 10.1016/j.phytol.2014.02.004 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84896311465&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/45722
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nigrolineabiphenyl B (4); and four xanthones, 1,3,6-trihydroxy-8-isoprenyl-7- methoxyxanthone (5), morusignin K (6), 1,5-dihydroxyxanthone (7), and 1,7-dihydroxyxanthone (8), were isolated from the acetone extract of the twigs of a Garcinia sp. Their structures were characterized extensively by 1D and 2D NMR spectroscopy and HR-EI-MS. The cytotoxicity of the two new biphenyls against the oral cavity cancer (KB) and the breast cancer (MCF7) cell lines was also evaluated. © 2014 Phytochemical Society of Europe.
format Journal
author Ittipon Siridechakorn
Wisanu Maneerat
Tawanun Sripisut
Thunwadee Ritthiwigrom
Sarot Cheenpracha
Surat Laphookhieo
spellingShingle Ittipon Siridechakorn
Wisanu Maneerat
Tawanun Sripisut
Thunwadee Ritthiwigrom
Sarot Cheenpracha
Surat Laphookhieo
Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
author_facet Ittipon Siridechakorn
Wisanu Maneerat
Tawanun Sripisut
Thunwadee Ritthiwigrom
Sarot Cheenpracha
Surat Laphookhieo
author_sort Ittipon Siridechakorn
title Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_short Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_full Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_fullStr Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_full_unstemmed Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_sort biphenyl and xanthone derivatives from the twigs of a garcinia sp. (clusiaceae)
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84896311465&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/45722
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