Root dentin anomaly and a PLG mutation

© 2014 Elsevier Masson SAS. We report a Thai girl affected with plasminogen deficiency, Type I. Ligneous conjunctivitis was first observed when she was one-month-old. The newly recognized findings include tapered incisor roots as a result of thin root dentin, generalized short tooth roots, and mandi...

Full description

Saved in:

Bibliographic Details
Main Authors:	Napaporn Tananuvat, Pimlak Charoenkwan, Atsushi Ohazama, James R. Ketuda Cairns, Massupa Kaewgahya, Piranit Nik Kantaputra
Format:	Journal
Published:	2018
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84918834387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/45766
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Chiang Mai University

id	th-cmuir.6653943832-45766
record_format	dspace
spelling	th-cmuir.6653943832-457662018-01-24T06:17:11Z Root dentin anomaly and a PLG mutation Napaporn Tananuvat Pimlak Charoenkwan Atsushi Ohazama James R. Ketuda Cairns Massupa Kaewgahya Piranit Nik Kantaputra © 2014 Elsevier Masson SAS. We report a Thai girl affected with plasminogen deficiency, Type I. Ligneous conjunctivitis was first observed when she was one-month-old. The newly recognized findings include tapered incisor roots as a result of thin root dentin, generalized short tooth roots, and mandibular prognathism. Mutation analysis of PLG demonstrated homozygous c.1193G > A missense mutation. The parents were heterozygous for c.1193G > A mutation. The c.1193G > A mutation is novel and predicted to cause amino acid substitution p.Cys398Tyr. Thin root dentin in the patient who was affected with PLG mutation and immunolocalization of Plg during early root development in mice imply the role of plasminogen in root dentin formation. 2018-01-24T06:17:11Z 2018-01-24T06:17:11Z 2014-01-01 Journal 18780849 17697212 2-s2.0-84918834387 10.1016/j.ejmg.2014.09.006 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84918834387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/45766
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
description	© 2014 Elsevier Masson SAS. We report a Thai girl affected with plasminogen deficiency, Type I. Ligneous conjunctivitis was first observed when she was one-month-old. The newly recognized findings include tapered incisor roots as a result of thin root dentin, generalized short tooth roots, and mandibular prognathism. Mutation analysis of PLG demonstrated homozygous c.1193G > A missense mutation. The parents were heterozygous for c.1193G > A mutation. The c.1193G > A mutation is novel and predicted to cause amino acid substitution p.Cys398Tyr. Thin root dentin in the patient who was affected with PLG mutation and immunolocalization of Plg during early root development in mice imply the role of plasminogen in root dentin formation.
format	Journal
author	Napaporn Tananuvat Pimlak Charoenkwan Atsushi Ohazama James R. Ketuda Cairns Massupa Kaewgahya Piranit Nik Kantaputra
spellingShingle	Napaporn Tananuvat Pimlak Charoenkwan Atsushi Ohazama James R. Ketuda Cairns Massupa Kaewgahya Piranit Nik Kantaputra Root dentin anomaly and a PLG mutation
author_facet	Napaporn Tananuvat Pimlak Charoenkwan Atsushi Ohazama James R. Ketuda Cairns Massupa Kaewgahya Piranit Nik Kantaputra
author_sort	Napaporn Tananuvat
title	Root dentin anomaly and a PLG mutation
title_short	Root dentin anomaly and a PLG mutation
title_full	Root dentin anomaly and a PLG mutation
title_fullStr	Root dentin anomaly and a PLG mutation
title_full_unstemmed	Root dentin anomaly and a PLG mutation
title_sort	root dentin anomaly and a plg mutation
publishDate	2018
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84918834387&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/45766
_version_	1681422806411116544

Root dentin anomaly and a PLG mutation

Similar Items