Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract
The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H2O2 scavenging assay. Polyphenolic; total phenolic, flavo...
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th-cmuir.6653943832-46112014-08-30T02:42:39Z Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract Singhatong S. Leelarungrayub D. Chaiyasut C. The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H2O2 scavenging assay. Polyphenolic; total phenolic, flavonoids and tannins were measured. Anti-oxidative stress was studied in AAPH-oxidized blood and glutathione (GSH), and malondialdehyde (MDA) was evaluated. Results showed that antioxidant activities were 128.30 ± 0.13, 55.86 ± 0.01, and 463.49 ± 0.01 μmol Trolox/g extracted from ABTS, DPPH, and H2O2 scavenging methods. One gram of extract contained total phenol (325.63 ± 2.99 mg GE), flavonoids (521.98 ± 0.01 mg QE) and tannins (124.03 ± 0.46 g TE), including rutin and resocinol. In the blood system, a low concentration of extract inhibited MDA progression and improved GSH, which was in contrast to a high concentration with its toxicity effect. 2014-08-30T02:42:39Z 2014-08-30T02:42:39Z 2010 Article 19960875 http://www.scopus.com/inward/record.url?eid=2-s2.0-77954054479&partnerID=40&md5=d4e0db8d55654cdb5e90750234fae78e http://cmuir.cmu.ac.th/handle/6653943832/4611 English |
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The antioxidant activity of Artocarpus lakoocha heartwood extract was investigated from ethanol extraction by 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) decolorization, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and H2O2 scavenging assay. Polyphenolic; total phenolic, flavonoids and tannins were measured. Anti-oxidative stress was studied in AAPH-oxidized blood and glutathione (GSH), and malondialdehyde (MDA) was evaluated. Results showed that antioxidant activities were 128.30 ± 0.13, 55.86 ± 0.01, and 463.49 ± 0.01 μmol Trolox/g extracted from ABTS, DPPH, and H2O2 scavenging methods. One gram of extract contained total phenol (325.63 ± 2.99 mg GE), flavonoids (521.98 ± 0.01 mg QE) and tannins (124.03 ± 0.46 g TE), including rutin and resocinol. In the blood system, a low concentration of extract inhibited MDA progression and improved GSH, which was in contrast to a high concentration with its toxicity effect. |
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Article |
author |
Singhatong S. Leelarungrayub D. Chaiyasut C. |
spellingShingle |
Singhatong S. Leelarungrayub D. Chaiyasut C. Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
author_facet |
Singhatong S. Leelarungrayub D. Chaiyasut C. |
author_sort |
Singhatong S. |
title |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_short |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_full |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_fullStr |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_full_unstemmed |
Antioxidant and toxicity activities of Artocarpus lakoocha Roxb. heartwood extract |
title_sort |
antioxidant and toxicity activities of artocarpus lakoocha roxb. heartwood extract |
publishDate |
2014 |
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http://www.scopus.com/inward/record.url?eid=2-s2.0-77954054479&partnerID=40&md5=d4e0db8d55654cdb5e90750234fae78e http://cmuir.cmu.ac.th/handle/6653943832/4611 |
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