Effect of Duabanga grandiflora for human skin cells

The purpose of this investigation was to evaluate the effects of Duabanga grandiflora (Sonneratiaceae), which has been used as a traditional Thai medicine on human skin cells. The leaf extract of D. grandiflora actively affected several human skin cells such as skin whitening, anti-aging and anti-in...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Tsukiyama M., Sugita T., Kikuchi H., Yasuda Y., Arashima M., Okumura H., Lhieochaiphant S., Shoyama Y.
التنسيق: مقال
اللغة:English
منشور في: 2014
الوصول للمادة أونلاين:http://www.scopus.com/inward/record.url?eid=2-s2.0-77951680602&partnerID=40&md5=0278e30fe42865a3e5b8efeb3c8aa957
http://cmuir.cmu.ac.th/handle/6653943832/4614
الوسوم: إضافة وسم
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المؤسسة: Chiang Mai University
اللغة: English
الوصف
الملخص:The purpose of this investigation was to evaluate the effects of Duabanga grandiflora (Sonneratiaceae), which has been used as a traditional Thai medicine on human skin cells. The leaf extract of D. grandiflora actively affected several human skin cells such as skin whitening, anti-aging and anti-inflammation. It became evident that the extract stimulated the production of type III collagen. The crude extract was fractionated and analyzed for stimulation of type III collagen production, and finally by HPLC to isolate an active compound which was determined to be eugeniin by EI-mass, 13C NMR, 1H NMR and acidic hydrolysis. Eugeniin has strong dose dependent activity for type III collagen production, with this being the first example of stimulation activity for type III collagen production. © 2010 World Scientific Publishing Company & Institute for Advanced Research in Asian Science and Medicine.