Free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes

The Physic Nut seed oil extracted by screw pressing was assayed for free radical scavenging activity by DPPH and tyrosinase inhibition activity by the dopachrome methods. The oils gave both activities similar to vitamin C. The maximum loading of the oil in niosomes composed of Tween 61/cholesterol a...

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Main Authors: Manosroi A., Boonpisuttinant K., Winitchai S., Manosroi W., Manosroi J.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-80053533243&partnerID=40&md5=c3f57950adbd68abd9cfac06108648f6
http://cmuir.cmu.ac.th/handle/6653943832/4635
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-46352014-08-30T02:42:41Z Free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes Manosroi A. Boonpisuttinant K. Winitchai S. Manosroi W. Manosroi J. The Physic Nut seed oil extracted by screw pressing was assayed for free radical scavenging activity by DPPH and tyrosinase inhibition activity by the dopachrome methods. The oils gave both activities similar to vitamin C. The maximum loading of the oil in niosomes composed of Tween 61/cholesterol at 3:7 molar ratio prepared by chloroform film method with sonication was 1%w/v. The niosomes were stable at 28°C for 8 weeks with an average size determined by dynamic light scattering (DLS) of about 120 nm. The oil entrapped in niosomes gave higher scavenging and tyrosinase inhibition activity than the unentrapped oil of about 3-5 and 1-2 times (p <0.1), respectively. This study has indicated the potential enhancement of free radical scav enging activity and tyrosinase inhibition activity of Physic Nut oil by entrapping in niosomes. © 2011 Bentham Science Publishers. 2014-08-30T02:42:41Z 2014-08-30T02:42:41Z 2011 Article 15734137 10.2174/157341311797483709 http://www.scopus.com/inward/record.url?eid=2-s2.0-80053533243&partnerID=40&md5=c3f57950adbd68abd9cfac06108648f6 http://cmuir.cmu.ac.th/handle/6653943832/4635 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The Physic Nut seed oil extracted by screw pressing was assayed for free radical scavenging activity by DPPH and tyrosinase inhibition activity by the dopachrome methods. The oils gave both activities similar to vitamin C. The maximum loading of the oil in niosomes composed of Tween 61/cholesterol at 3:7 molar ratio prepared by chloroform film method with sonication was 1%w/v. The niosomes were stable at 28°C for 8 weeks with an average size determined by dynamic light scattering (DLS) of about 120 nm. The oil entrapped in niosomes gave higher scavenging and tyrosinase inhibition activity than the unentrapped oil of about 3-5 and 1-2 times (p <0.1), respectively. This study has indicated the potential enhancement of free radical scav enging activity and tyrosinase inhibition activity of Physic Nut oil by entrapping in niosomes. © 2011 Bentham Science Publishers.
format Article
author Manosroi A.
Boonpisuttinant K.
Winitchai S.
Manosroi W.
Manosroi J.
spellingShingle Manosroi A.
Boonpisuttinant K.
Winitchai S.
Manosroi W.
Manosroi J.
Free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes
author_facet Manosroi A.
Boonpisuttinant K.
Winitchai S.
Manosroi W.
Manosroi J.
author_sort Manosroi A.
title Free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes
title_short Free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes
title_full Free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes
title_fullStr Free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes
title_full_unstemmed Free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes
title_sort free radical scavenging and tyrosinase inhibition activity of physic nut (jatropha curcas linn.) seed oil entrapped in niosomes
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-80053533243&partnerID=40&md5=c3f57950adbd68abd9cfac06108648f6
http://cmuir.cmu.ac.th/handle/6653943832/4635
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