Rational Redesign of a Functional Protein Kinase-Substrate Interaction

• Main Authors: Catherine Chen, Wutigri Nimlamool, Chad J. Miller, Hua Jane Lou, Benjamin E. Turk
• Format: Journal
• Published: 2018
• Subjects: Agricultural and Biological Sciences
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85019583827&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/46394
• Institution: Chiang Mai University

© 2017 American Chemical Society. Eukaryotic protein kinases typically phosphorylate substrates in the context of specific sequence motifs, contributing to specificity essential for accurate signal transmission. Protein kinases recognize their target sequences through complementary interactions with...