Activation of melatonin receptor (MT1/2) promotes P-gp transporter in methamphetamine-induced toxicity on primary rat brain microvascular endothelial cells

• Main Authors: Pichaya Jumnongprakhon, Sivanan Sivasinprasasn, Piyarat Govitrapong, Chainarong Tocharus, Jiraporn Tocharus
• Format: Journal
• Published: 2018
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85013968602&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/47154
• Institution: Chiang Mai University

© 2017 Elsevier Ltd Melatonin has been known as a neuroprotective agent for the central nervous system (CNS) and the blood–brain barrier (BBB), which is the primary structure that comes into contact with several neurotoxins including methamphetamine (METH). Previous studies have reported that the ac...