Subtotal nephrectomy accelerates pathological cardiac remodeling post-myocardial infarction: Implications for cardiorenal syndrome

• Main Authors: Shan Liu, Andrew R. Kompa, Sirinart Kumfu, Fuyuhiko Nishijima, Darren J. Kelly, Henry Krum, Bing H. Wang
• Format: Journal
• Published: 2018
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84885667439&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/47604
• Institution: Chiang Mai University

Background To further understand the pathophysiology of concomitant cardiac and renal dysfunction, we investigated molecular, structural and functional changes in heart and kidney that occur when a kidney insult (5/6 nephrectomy-STNx) follows myocardial infarction (MI). Methods Male Sprague Dawley r...