Susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin
Susceptibility to metronidazole and vancomycin, drugs of choice for Clostridium difficile infection, of 15 C. difficile isolates from 6 healthy Asian elephants was determined. All of the isolates belonged to only 1 ribotype pattern and carried both toxin A and B genes. The Minimal inhibitory concent...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Journal |
| Published: |
2018
|
| Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84882582262&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/47701 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Chiang Mai University |
| id |
th-cmuir.6653943832-47701 |
|---|---|
| record_format |
dspace |
| spelling |
th-cmuir.6653943832-477012018-04-25T08:43:00Z Susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin Nattawooti Sthitmatee Thanya Warinrak Waroot Wongkalasin Susceptibility to metronidazole and vancomycin, drugs of choice for Clostridium difficile infection, of 15 C. difficile isolates from 6 healthy Asian elephants was determined. All of the isolates belonged to only 1 ribotype pattern and carried both toxin A and B genes. The Minimal inhibitory concentration range of metronidazole and vancomycin, drugs of choice for treatment of C. difficile infection, was 0.125-4.0 μg/ml and 0.125-2.0 μg/ml, respectively. Moreover, MIC50 and MIC90 for metronidazole were 0.75 and 1.5 μg/ml while vancomycin was 1.0 and 2.0 μg/ml. There was no evidence of resistance to these antimicrobials. These results might be a preliminary data for further study of animal C. difficile. 2018-04-25T08:43:00Z 2018-04-25T08:43:00Z 2013-08-27 Journal 01256491 2-s2.0-84882582262 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84882582262&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/47701 |
| institution |
Chiang Mai University |
| building |
Chiang Mai University Library |
| country |
Thailand |
| collection |
CMU Intellectual Repository |
| description |
Susceptibility to metronidazole and vancomycin, drugs of choice for Clostridium difficile infection, of 15 C. difficile isolates from 6 healthy Asian elephants was determined. All of the isolates belonged to only 1 ribotype pattern and carried both toxin A and B genes. The Minimal inhibitory concentration range of metronidazole and vancomycin, drugs of choice for treatment of C. difficile infection, was 0.125-4.0 μg/ml and 0.125-2.0 μg/ml, respectively. Moreover, MIC50 and MIC90 for metronidazole were 0.75 and 1.5 μg/ml while vancomycin was 1.0 and 2.0 μg/ml. There was no evidence of resistance to these antimicrobials. These results might be a preliminary data for further study of animal C. difficile. |
| format |
Journal |
| author |
Nattawooti Sthitmatee Thanya Warinrak Waroot Wongkalasin |
| spellingShingle |
Nattawooti Sthitmatee Thanya Warinrak Waroot Wongkalasin Susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin |
| author_facet |
Nattawooti Sthitmatee Thanya Warinrak Waroot Wongkalasin |
| author_sort |
Nattawooti Sthitmatee |
| title |
Susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin |
| title_short |
Susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin |
| title_full |
Susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin |
| title_fullStr |
Susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin |
| title_full_unstemmed |
Susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin |
| title_sort |
susceptibility of clostridium difficile isolated from healthy captive asian elephants to metronidazole and vancomycin |
| publishDate |
2018 |
| url |
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84882582262&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/47701 |
| _version_ |
1681423110931218432 |