Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)

Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)

The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nig...

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Main Authors: Siridechakorn I., Maneerat W., Sripisut T., Ritthiwigrom T., Cheenpracha S., Laphookhieo S.
Format: Article
Language:English
Published: Elsevier BV 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84896311465&partnerID=40&md5=0f58e7555091a1f9458098c2513e0d60
http://cmuir.cmu.ac.th/handle/6653943832/4783
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-47832014-08-30T02:55:45Z Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae) Siridechakorn I. Maneerat W. Sripisut T. Ritthiwigrom T. Cheenpracha S. Laphookhieo S. The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nigrolineabiphenyl B (4); and four xanthones, 1,3,6-trihydroxy-8-isoprenyl-7- methoxyxanthone (5), morusignin K (6), 1,5-dihydroxyxanthone (7), and 1,7-dihydroxyxanthone (8), were isolated from the acetone extract of the twigs of a Garcinia sp. Their structures were characterized extensively by 1D and 2D NMR spectroscopy and HR-EI-MS. The cytotoxicity of the two new biphenyls against the oral cavity cancer (KB) and the breast cancer (MCF7) cell lines was also evaluated. © 2014 Phytochemical Society of Europe. 2014-08-30T02:55:45Z 2014-08-30T02:55:45Z 2014 Article 18767486 10.1016/j.phytol.2014.02.004 PLHEB http://www.scopus.com/inward/record.url?eid=2-s2.0-84896311465&partnerID=40&md5=0f58e7555091a1f9458098c2513e0d60 http://cmuir.cmu.ac.th/handle/6653943832/4783 English Elsevier BV
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The genus Garcinia is a well known rich source of bioactive xanthones and benzophenones. Some species of this genus also produce flavonoids and biphenyls as minor constituents. In this study, two new biphenyls, doitungbiphenyls A (1) and B (2), along with two biphenyls, schomburgbiphenyl (3) and nigrolineabiphenyl B (4); and four xanthones, 1,3,6-trihydroxy-8-isoprenyl-7- methoxyxanthone (5), morusignin K (6), 1,5-dihydroxyxanthone (7), and 1,7-dihydroxyxanthone (8), were isolated from the acetone extract of the twigs of a Garcinia sp. Their structures were characterized extensively by 1D and 2D NMR spectroscopy and HR-EI-MS. The cytotoxicity of the two new biphenyls against the oral cavity cancer (KB) and the breast cancer (MCF7) cell lines was also evaluated. © 2014 Phytochemical Society of Europe.
format Article
author Siridechakorn I.
Maneerat W.
Sripisut T.
Ritthiwigrom T.
Cheenpracha S.
Laphookhieo S.
spellingShingle Siridechakorn I.
Maneerat W.
Sripisut T.
Ritthiwigrom T.
Cheenpracha S.
Laphookhieo S.
Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
author_facet Siridechakorn I.
Maneerat W.
Sripisut T.
Ritthiwigrom T.
Cheenpracha S.
Laphookhieo S.
author_sort Siridechakorn I.
title Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_short Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_full Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_fullStr Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_full_unstemmed Biphenyl and xanthone derivatives from the twigs of a Garcinia sp. (Clusiaceae)
title_sort biphenyl and xanthone derivatives from the twigs of a garcinia sp. (clusiaceae)
publisher Elsevier BV
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-84896311465&partnerID=40&md5=0f58e7555091a1f9458098c2513e0d60
http://cmuir.cmu.ac.th/handle/6653943832/4783
_version_ 1681420302315159552

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