Inhibition of p38 MAPK during ischemia, but not reperfusion, effectively attenuates fatal arrhythmia in ischemia/reperfusion heart

ABSTRACT:: The mitogen-activated protein kinases (MAPKs) play an important role in ischemia/reperfusion (I/R) injury. Previous evidence suggests that p38 MAPK inhibition before ischemia is cardioprotective. However, whether p38 MAPK inhibition during ischemia or reperfusion provides cardioprotection...

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Bibliographic Details
Main Authors: Sirirat Surinkaew, Sarawut Kumphune, Siriporn Chattipakorn, Nipon Chattipakorn
Format: Journal
Published: 2018
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84873407517&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/48133
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Institution: Chiang Mai University