Phenylpropanoid derivatives from Clausena harmandiana fruits

A new phenylpropanoid derivative, harmandianone (1), along with four known compounds: verimol B (2), (E)-3-(2-hydroxy-4-methoxy-phenyl)propanoate (3), (E)-methyl p-coumarate (4), and (E)-5-methoxy-2-(prop-1-enyl)phenol (5) was isolated from the acetone extract of Clausena harmandiana fruits. All str...

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Main Authors: Wisanu Maneerat, Wong Phakhodee, Thunwadee Ritthiwigrom, Sarot Cheenpracha, Suwanna Deachathai, Surat Laphookhieo
Format: Journal
Published: 2018
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84868455715&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/48134
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-481342018-04-25T08:48:05Z Phenylpropanoid derivatives from Clausena harmandiana fruits Wisanu Maneerat Wong Phakhodee Thunwadee Ritthiwigrom Sarot Cheenpracha Suwanna Deachathai Surat Laphookhieo A new phenylpropanoid derivative, harmandianone (1), along with four known compounds: verimol B (2), (E)-3-(2-hydroxy-4-methoxy-phenyl)propanoate (3), (E)-methyl p-coumarate (4), and (E)-5-methoxy-2-(prop-1-enyl)phenol (5) was isolated from the acetone extract of Clausena harmandiana fruits. All structures were characterized by spectroscopic methods (UV, IR, NMR and ESI-TOF-MS). Compounds 1 and 3-5 demonstrated weak antibacterial activity against Escherichia coli TISTR 780, methicillin-resistant Staphylococcus aureus SK1, Salmonella typhimurium TISTR 292 and S. aureus TISTR1466, with MIC values between 64 and 128 μg/mL.Copyright © 2012 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. 2018-04-25T08:48:05Z 2018-04-25T08:48:05Z 2013-02-01 Journal 18767486 18743900 2-s2.0-84868455715 10.1016/j.phytol.2012.10.006 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84868455715&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/48134
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
description A new phenylpropanoid derivative, harmandianone (1), along with four known compounds: verimol B (2), (E)-3-(2-hydroxy-4-methoxy-phenyl)propanoate (3), (E)-methyl p-coumarate (4), and (E)-5-methoxy-2-(prop-1-enyl)phenol (5) was isolated from the acetone extract of Clausena harmandiana fruits. All structures were characterized by spectroscopic methods (UV, IR, NMR and ESI-TOF-MS). Compounds 1 and 3-5 demonstrated weak antibacterial activity against Escherichia coli TISTR 780, methicillin-resistant Staphylococcus aureus SK1, Salmonella typhimurium TISTR 292 and S. aureus TISTR1466, with MIC values between 64 and 128 μg/mL.Copyright © 2012 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
format Journal
author Wisanu Maneerat
Wong Phakhodee
Thunwadee Ritthiwigrom
Sarot Cheenpracha
Suwanna Deachathai
Surat Laphookhieo
spellingShingle Wisanu Maneerat
Wong Phakhodee
Thunwadee Ritthiwigrom
Sarot Cheenpracha
Suwanna Deachathai
Surat Laphookhieo
Phenylpropanoid derivatives from Clausena harmandiana fruits
author_facet Wisanu Maneerat
Wong Phakhodee
Thunwadee Ritthiwigrom
Sarot Cheenpracha
Suwanna Deachathai
Surat Laphookhieo
author_sort Wisanu Maneerat
title Phenylpropanoid derivatives from Clausena harmandiana fruits
title_short Phenylpropanoid derivatives from Clausena harmandiana fruits
title_full Phenylpropanoid derivatives from Clausena harmandiana fruits
title_fullStr Phenylpropanoid derivatives from Clausena harmandiana fruits
title_full_unstemmed Phenylpropanoid derivatives from Clausena harmandiana fruits
title_sort phenylpropanoid derivatives from clausena harmandiana fruits
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84868455715&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/48134
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