How to manage unresponsiveness to misoprostol in failed second trimester pregnancy termination
Aim: To present the experience of management of second trimester pregnancy termination by misoprostol after failure to abort within 48 h of its use. Material and Methods: A retrospective, cohort descriptive study was carried out in the Department of Obstetrics and Gynecology, Faculty of Medicine, Ch...
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| Main Authors: | , |
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| Format: | Journal |
| Published: |
2018
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| Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84875723465&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/48195 |
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| Institution: | Chiang Mai University |
| Summary: | Aim: To present the experience of management of second trimester pregnancy termination by misoprostol after failure to abort within 48 h of its use. Material and Methods: A retrospective, cohort descriptive study was carried out in the Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University Thailand between 1998 and 2010. All women at 14-28 weeks of gestation who failed to abort using misoprostol within 48 h were included. Management of failed pregnancy termination among these women is described here. Results: Of a total of 680 women undergoing termination of pregnancy, 68 (10%) failed to abort. Mean maternal age was 28.71 years and mean gestational age was 19.91 weeks. Further management after failure included additional administration of misoprostol only (19.1%), modified condom balloon technique only (17.7%), modified condom balloon technique plus other methods (16.1%), while 47.1% needed only oxytocin as necessary. The mean interval between initiation of termination and delivery was 96.97 h. Conclusion: Failure of pregnancy termination using misoprostol can be successfully managed by introducing additional misoprostol, modified condom balloon technique and oxytocin infusion. These methods should be considered before proceeding to hysterotomy. © 2012 The Authors. |
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