Adherence to antiretroviral therapy and acceptability of planned treatment interruptions in HIV-infected children

• Main Authors: Linda Harrison, Jintanat Ananworanich, Djamel Hamadache, Alexandra Compagnucci, Martina Penazzato, Torsak Bunupuradah, Antonio Mazza, Jose Tomas Ramos, Jacquie Flynn, Osvalda Rampon, Maria Jose Mellado Pena, Daniel Floret, Magdalena Marczynska, Ana Puga, Silvia Forcat, Yoann Riault, Marc Lallemant, Hannah Castro, Diana M. Gibb, Carlo Giaquinto
• Format: Journal
• Published: 2018
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84872684621&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/48354
• Institution: Chiang Mai University

There have been no paediatric randomised trials describing the effect of planned treatment interruptions (PTIs) of antiretroviral therapy (ART) on adherence, or evaluating acceptability of such a strategy. In PENTA 11, HIV-infected children were randomised to CD4-guided PTIs (n = 53) or continuous t...