Prevalence of CYP2C9 and VKORC1 mutation in patients with valvular heart disease in Northern Thailand

• المؤلفون الرئيسيون: Srun Kuanprasert, Sakchai Dettrairat, Poonsub Palacajornsuk, Warunee Kunachiwa, Arintaya Phrommintikul
• التنسيق: دورية
• منشور في: 2018
• الموضوعات: Medicine
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77249097871&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49265
• المؤسسة: Chiang Mai University

Background: Warfarin has been widely used for the prevention and treatment of thromboembolism. Warfarin therapy depends on interaction between physiological, environmental, and genetic factors. Vitamin K epoxide reductase (VKORC1) and cytochrome P450 2C9 (CYP2C9) enzyme conjointly determine the warf...