Plasma efavirenz concentrations and the association with CYP2B6-516G>T polymorphism in HIV-infected Thai Children

Background: Concerns have been raised about the possibility of subtherapeutic efavirenz (EFV) plasma levels in children with the current dosing guideline. Single nucleotide polymorphisms of the hepatic cytochrome P450 isoenzyme 2B6 (CYP2B6) gene have been associated with high interindividual variati...

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Bibliographic Details
Main Authors: Thanyawee Puthanakit, Pranoot Tanpaiboom, Linda Aurpibul, Tim R. Cressey, Virat Sirisanthana
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67649177436&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49331
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Institution: Chiang Mai University