P-glycoprotein-mediated efflux and drug sequestration in lysosomes confer advantages of K562 multidrug resistance sublines to survive prolonged exposure to cytotoxic agents

Problem statement: Cellular drug resistance to anticancer agents is major obstacle in cancer chemotherapy and the mechanisms by which these MDR cells possess for protecting themselves to survive prolonged exposure to cytotoxic agents still debating. The study aimed to clarify the role of P-glycoprot...

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Bibliographic Details
Main Authors: Nathupakorn Dechsupa, Samlee Mankhetkorn
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70350026416&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49484
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Institution: Chiang Mai University