P-glycoprotein-mediated efflux and drug sequestration in lysosomes confer advantages of K562 multidrug resistance sublines to survive prolonged exposure to cytotoxic agents
Problem statement: Cellular drug resistance to anticancer agents is major obstacle in cancer chemotherapy and the mechanisms by which these MDR cells possess for protecting themselves to survive prolonged exposure to cytotoxic agents still debating. The study aimed to clarify the role of P-glycoprot...
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Main Authors: | , |
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Format: | Journal |
Published: |
2018
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Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70350026416&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/49484 |
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Institution: | Chiang Mai University |