Acute and subchronic toxicity study of the water extract from Harrisonia perforata Merr. in rats

• Main Authors: Seewaboon Sireeratawong, Nirush Lertprasertsuke, Umarat Srisawat, Amornat Thuppia, Anongnad Ngamjariyawat, Nadthaganya Suwanlikhid, Kanjana Jaijoy
• Format: Journal
• Published: 2018
• Subjects: Multidisciplinary
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=67650928346&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49514
• Institution: Chiang Mai University

The water extract from Harrisonia perforata Merr. was studied for acute and subchronic toxicities. The extract at a single dose of 5,000 mg/kg was administered orally to female and male rats (5 males, 5 females). After 14 days, signs and behavioral changes, mortality, gross and histopathological cha...