The effect of methoxyflavone on P-glycoprotein-mediated transport and intracellular reactive oxygen species in cancer cells

• Main Authors: Jirapha Keeddee, Numpol Rattanaworasin, Montree Tungjai
• Format: Journal
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80052739740&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49640
• Institution: Chiang Mai University

The natural products have been reported to exhibit anticancer and antioxidant activities. The aim of this study was to determine the effect of 5,4′-dihydroxy-3,6,7,8-tetramethoxyflavone (WP279), 5,5′-dihydroxy- 6,7,3′,4′-tetramethoxyflavone (WP280) and 5,3′-dihydroxy-3,6, 7,8,4′-pentamethoxyflavone(...