Induction of G1 arrest and apoptosis in androgen-dependent human prostate cancer by Kuguacin J, a triterpenoid from Momordica charantia leaf

Induction of G1 arrest and apoptosis in androgen-dependent human prostate cancer by Kuguacin J, a triterpenoid from Momordica charantia leaf

In this study, we focused on the effects of a bitter melon (Momordica charantia) leaf extract (BMLE) and a purified component, Kuguacin J (KuJ), on androgen-dependent LNCaP human prostate cancer cells. Both treatments exerted growth inhibition through G1 arrest and induction of apoptosis. In additio...

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Bibliographic Details
Main Authors: Pornsiri Pitchakarn, Shugo Suzuki, Kumiko Ogawa, Wilart Pompimon, Satoru Takahashi, Makoto Asamoto, Pornngarm Limtrakul, Tomoyuki Shirai
Format: Journal
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79955465233&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49700
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Institution: Chiang Mai University

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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79955465233&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/49700

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