Effects of nobiletin on PhIP-induced prostate and colon carcinogenesis in F344 rats

• Main Authors: Ming Xi Tang, Kumiko Ogawa, Makoto Asamoto, Teera Chewonarin, Shugo Suzuki, Takuji Tanaka, Tomoyuki Shirai
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79951884253&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49742
• Institution: Chiang Mai University

The current study was designed to investigate the effects of nobiletin (5,6,7,8,3′,4′-hexamethoxy flavone) on 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP)-induced prostate and colon carcinogenesis. PhIP was administered to 6-wk-old F344 male rats intragastrically (100 mg/kg) twice a wk fo...