Fibroblast and Vascular Endothelial Growth Factor Coating of Decellularized Vascular Grafts Stimulates Undesired Giant Cells and Graft Encapsulation in a Rat Model

• Main Authors: Christoph Heidenhain, Ariyakhagorn Veeravoorn, Blagovest Vachkov, Wilko Weichert, Gerhard Schmidmaier, Britt Wildemann, Peter Neuhaus, Michael Heise
• Format: Journal
• Published: 2018
• Subjects: Chemical Engineering; Engineering; Materials Science; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=78651418247&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/49801
• Institution: Chiang Mai University

Replacing an infected prosthesis with a bioimplant provides a hopeful alternative in septic vascular surgery. The objective of this study was to determine the effect of fibroblast endothelial growth factors (FGF) and vascular endothelial growth factors (VEGF) coating on a decellularized vascular gra...